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Merck

T-909

Supelco

α-Hydroxytriazolam-d4 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C17D4H8Cl2N4O
Número de CAS:
Peso molecular:
363.23
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

OCC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=C([2H])C([2H])=C([2H])C([2H])=C4Cl)=NC2

InChI

1S/C17H12Cl2N4O/c18-10-5-6-14-12(7-10)17(11-3-1-2-4-13(11)19)20-8-15-21-22-16(9-24)23(14)15/h1-7,24H,8-9H2/i1D,2D,3D,4D

Inchi Key

BHUYWUDMVCLHND-RHQRLBAQSA-N

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General description

a-Hydroxytriazolam is a major urinary and blood metabolite of the benzodiazepine, triazolam, a pharmaceutical used to treat severe insomnia. This stable-labeled internal standard is suitable for triazolam testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, urine drug testing, pain prescription monitoring or forensic analysis.

Application


  • Pharmacokinetic Analysis of α-Hydroxytriazolam: A study focused on the urinary excretion of α-Hydroxytriazolam following a single dose of Halcion. This research provides critical insights into the metabolism of benzodiazepines, emphasizing the role of α-Hydroxytriazolam-d₄ as a stable isotope-labeled standard in tracing metabolic pathways in clinical pharmacology (Lin et al., 2005).

  • Forensic Toxicology and Metabolite Confirmation: Another significant study utilized GC-MS to confirm the presence of urinary benzodiazepine metabolites, including α-Hydroxytriazolam. This research underscores the utility of α-Hydroxytriazolam-d₄ in forensic analysis, aiding in the detection and confirmation of benzodiazepine use and abuse in legal and medical settings (Meatherall, 1994).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Certificados de análisis (COA)

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