D-010

1,2-Dinitroglycerin solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₃H₆N₂O₇
• Número de CAS: 621-65-8
• Peso molecular: 182.09
• Número CE: 200-835-2
• Número MDL: MFCD00661060
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329798580
• NACRES: NA.24

Propiedades

• grado: certified reference material
• Nivel de calidad: 300
• Formulario: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• concentración: 1.0 mg/mL in acetonitrile
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: pharmaceutical (small molecule)
• Formato: single component solution
• temp. de almacenamiento: −20°C
• cadena SMILES: OC[C@@H](O[N+]([O-])=O)CO[N+]([O-])=O
• InChI: 1S/C3H6N2O7/c6-1-3(12-5(9)10)2-11-4(7)8/h3,6H,1-2H2
• Clave InChI: GFVHBTOOPNJKLV-UHFFFAOYSA-N

Descripción

Descripción general

1,2-Dinitroglycerin is a major plasma metabolite of the pharmaceutical vasodilator nitroglycerin. This Certified Spiking Solution^® is suitable for use in chromatography or mass spectrometry-based applications in pharmaceutical research or clinical toxicology. Nitroglycerin is used to treat heart conditions such as angina and chronic heart failure.

Aplicación

• Pharmacokinetics of transdermal nitroglycerin: Research demonstrates the pharmacokinetic profiling of nitroglycerin and its metabolites from a transdermal delivery system, including 1,2-Dinitroglycerin, which contributes to its sustained release and absorption characteristics. This study supports its use in controlled drug delivery applications (Auclair et al., 1998).



• Nitroglycerin metabolism research: Analytical techniques for studying the metabolism of nitroglycerin, including the role of 1,2-Dinitroglycerin, were detailed, highlighting methods for examining nitrite and glutathione interactions. This research aids in understanding the metabolic pathways and implications of nitroglycerin derivatives in pharmacology (Curry et al., 1987).

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H225,H302 + H312 + H332,H319
• Consejos de prudencia: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 35.6 °F - closed cup
• Punto de inflamabilidad (°C): 2 °C - closed cup