20023

O-tert-Butylhydroxylamine hydrochloride

≥99.0% (AT)

• Sinónimos: 2-Aminooxy-2-methylpropane hydrochloride, O-(1,1-Dimethylethyl)hydroxylamine hydrochloride, tert-Butoxyamine hydrochloride
• Fórmula lineal: (CH₃)₃CONH₂ · HCl
• Número de CAS: 39684-28-1
• Peso molecular: 125.60
• Beilstein: 3668106
• Número CE: 254-590-1
• Número MDL: MFCD00043272
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 57647770
• NACRES: NA.22

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥99.0% (AT)
• Formulario: solid
• mp: ~155 °C (dec.)
• solubilidad: H₂O: soluble 0.5 g/10 mL
• cadena SMILES: Cl.CC(C)(C)ON
• InChI: 1S/C4H11NO.ClH/c1-4(2,3)6-5;/h5H2,1-3H3;1H
• Clave InChI: ZBDXGNXNXXPKJI-UHFFFAOYSA-N

Descripción

Aplicación

O-tert-Butylhydroxylamine hydrochloride was used in the synthesis of N-methyl-O-tert-butylhydroxylamine hydrochloride. It was also used in the preparation of N-tert-butoxyamino acids as substrates for the unambiguous synthesis of N-hydroxy peptides.

Reactant involved in synthesis of biologically active molecules including:

• CGS 25966 derivatives for use as MMP inhibitors
• Imidazolidinedione derivatives for use as antimalarial treatments
• Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists
• Rab proteins for isoprenylation and geranylgeranylation inhibition

Reactant involved in:

• Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents
• Double allylic alkylation of indole-2-hydroxamates
• SN2 substitution reactions at amide nitrogens
• Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines

Información de seguridad

• Pictogramas: GHS02
• Palabra de señalización: Warning
• Frases de peligro: H228
• Consejos de prudencia: P210
• Clasificaciones de peligro: Flam. Sol. 2
• Código de clase de almacenamiento: 4.1B - Flammable solid hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges