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181986

Sigma-Aldrich

Poly(ethylene oxide)

average MV 100,000 (nominal), powder, hydroxyl, BHT as inhibitor

Sinónimos:

Polyethylene oxide, PEO

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About This Item

Fórmula lineal:
(-CH2CH2O-)n
Número de CAS:
25322-68-3
Número MDL:
MFCD00081839
Código UNSPSC:
12352104
ID de la sustancia en PubChem:
24850968
NACRES:
NA.23
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Nombre del producto

Poly(ethylene oxide), average Mv 100,000 (nominal), powder

Formulario

powder

Nivel de calidad

200

mol peso

average Mv 100,000 (nominal)

contiene

200-500 ppm BHT as inhibitor

índice de refracción

n20/D 1.4539

viscosidad

12-50 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

temperatura de transición

Tg −67 °C
Tm 65 °C

densidad

1.13 g/mL at 25 °C

Ω-final

hydroxyl

α-final

hydroxyl

cadena SMILES

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clave InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descripción general

Poly(ethylene oxide) is a non-ionic hydrophilic linear polymer. It can be prepared by catalytic polymerization of ethylene oxide. Owing to its hydration and swelling properties, it is widely used in controlled drug delivery systems and bioadhesive materials.

Aplicación

PEO can be used to:
  • Prepare polymer brushes with unique wormlike conformation which can be used in cancer drug delivery systems.
  • Synthesize polymer electrolytes for solid-state batteries and fuel cells.
  • Prepare biodegradable PEO/Ag nanocomposites forbiomedical and food packaging applications.

Características y beneficios

  • High water solubility
  • Non-toxicity
  • Rapid hydration
  • Insensitive to pH of the physiological system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCW8707
MKCV7727
MKCW2937
MKCT9842
MKCT4963

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Wang, X.-L., et al.
Jiangsu Huagong, 32, 27-27 (2004)
Alexandre Goyon et al.
Electrophoresis, 39(16), 2083-2090 (2018-05-19)
The determination of mAb critical quality attributes (CQA) is crucial for their successful application in health diseases. A generic CZE method was developed for the high-resolution separation of various mAb charge variants, which are often recognized as important CQA. A
Yeonsu Jung et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(3) (2021-01-13)
Mud nests built by swallows (Hirundinidae) and phoebes (Sayornis) are stable granular piles attached to cliffs, walls, or ceilings. Although these birds have been observed to mix saliva with incohesive mud granules, how such biopolymer solutions provide the nest with
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

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Versatile Cell Culture Scaffolds: Bio-orthogonal Click

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Questions

1–7 of 7 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. I would like to obtain specific information regarding PEO with a nominal molecular weight of 100,000: Is it compostable? The reason for this question is related to a research project I am conducting on this compound. Thank you for your attention

    1 answer

    1. There is no official pronouncement indicating that Product 181986, Poly(ethylene oxide), is a compostable material obtained.
      Please note the following information below from the Safety Data Sheet that appears to touch on this question:

      Section 2.1 Classification of the substance or mixture
      "Not a hazardous substance or mixture according to the Globally Harmonized System (GHS)."

      Section 12.2 Persistence and degradability
      "Biodegradability aerobic - Exposure time 28 d
      Result: 74.85 % - Readily biodegradable.
      (OECD Test Guideline 301D)"

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  4. What are the endgroups of this particular Poly(ethylene oxide), Product 181986?

    1 answer

    1. According to our supplier, the end groups of this product are hydroxy groups.

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  5. What is the polydispersity of Poly(ethylene oxide), Product 181986?

    1 answer

    1. Unfortunately, our supplier has not determined the polydispersity of this product and it is not part of our specifications.

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  6. What is the solubility of Poly(ethylene oxide), Product 181986?

    1 answer

    1. According to the chemicals encyclopedia published by the Royal Society of Chemistry:13th Edition, this product is soluble in water and many organic solvents.

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  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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