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159158

Sigma-Aldrich

Acetamidine hydrochloride

95%

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About This Item

Fórmula lineal:
CH3C(=NH)NH2 · HCl
Número de CAS:
124-42-5
Peso molecular:
94.54
Beilstein/REAXYS Number:
3591762
EC Number:
204-700-9
MDL number:
MFCD00013016
UNSPSC Code:
12352100
PubChem Substance ID:
24849795
NACRES:
NA.22

assay

95%

form

solid

mp

165-170 °C (lit.)

SMILES string

Cl[H].CC(N)=N

InChI

1S/C2H6N2.ClH/c1-2(3)4;/h1H3,(H3,3,4);1H

InChI key

WCQOBLXWLRDEQA-UHFFFAOYSA-N

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General description

Acetamidine hydrochloride is an amidine salt and its conversion to 2,4,6-trimethyl-sym-triazine has been studied.

Application

Acetamidine hydrochloride was used in the preparation of decarboxyectoine. It was also used in the synthesis of ethyl 4-(4-hydroxyphenyl)methylidene-2-methyl-5-oxo-1-imidazolacetate.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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H Niwa et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(24), 13617-13622 (1996-11-26)
The jellyfish Aequorea victoria possesses in the margin of its umbrella a green fluorescent protein (GFP, 27 kDa) that serves as the ultimate light emitter in the bioluminescence reaction of the animal. The protein is made up of 238 amino
Synthesis of the sym-Triazine System. I. Trimerization and Cotrimerization of Amidines.
Schaefer FC, et al.
Journal of the American Chemical Society, 81(6), 1466-1470 (1959)
Michael Schnoor et al.
Biochemical and biophysical research communications, 322(3), 867-872 (2004-09-01)
Different substances such as dimethyl sulfoxide, tetramethylene sulfoxide, 2-pyrollidone, and the naturally occurring compatible solute betaine enhance PCR amplification of GC-rich DNA templates with high melting temperatures. In particular, cyclic compatible solutes outperform traditional PCR enhancers. We therefore investigated the
Jin Sheng Guo et al.
European journal of pharmacology, 536(3), 301-308 (2006-04-08)
Nitric oxide synthases (NOS) and cyclooxygenase-2 (COX-2) are important enzymes involved in ulcer healing but interactions between them have not been clearly defined. The aim of this study was to investigate the effects of selective or non-selective inhibition of NOS
Cristina Maccallini et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 8(6), 991-995 (2012-06-30)
A new series of phenyl- and heteryl acetamidines were synthesized and evaluated as inhibitors of nitric oxide synthases (NOS). While the N-substitution of the acetamidine moiety with different heterocycles appears to completely destroy the activity, linking the phenyl core preserves
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