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PHR1196

Supelco

Nitrofurazone

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

5-Nitro-2-furaldehyde semicarbazone, NZ, Nitrofural, 5-Nitro-2-furfural semicarbazone, Furacin, NFZ, Nitrofurazone

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About This Item

Formule empirique (notation de Hill):
C6H6N4O4
Numéro CAS:
59-87-0
Poids moléculaire :
198.14
Numéro Beilstein :
86403
Numéro CE :
200-443-1
Numéro MDL:
MFCD00003225
Code UNSPSC :
41116107
ID de substance PubChem :
329823204
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

300

Agence

traceable to Ph. Eur. N0950000
traceable to USP 1465004

Famille d'API

nitrofurazone

CofA (certificat d'analyse)

current certificate can be downloaded

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Pf

242-244 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

Clé InChI

IAIWVQXQOWNYOU-FPYGCLRLSA-N

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Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Nitrofurazone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by DC polarography, chromatography and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC0296 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2

Organes cibles

male reproductive organs

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number
LRAD7003
LRAD4452
LRAC0296
LRAA9012
P500196

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Electrochemical reduction of nitrofurazone and its determination in pharmaceutical dosage forms by Dc polarography
Mishra AK and Gode KD
Analyst, 110(11), 1373-1376 (1985)
Inclusion compounds in pharmaceutical analysis II: Assay of a cream following chemical dehydration
Hays SE and Grady LT
Journal of Pharmaceutical Sciences, 60(2), 295-298 (1971)
Teresa del Castillo et al.
ChemMedChem, 9(2), 383-389 (2013-12-18)
Cyclodextrins have been conjugated to target various receptors and have also been functionalized with carbohydrates for targeting specific organs. However, this approach is based on a rigid design that implies the ad hoc synthesis of each cyclodextrin-targeting agent conjugate. We
Fengyu Deng et al.
Molecular bioSystems, 8(5), 1446-1451 (2012-02-18)
The interaction of nitrofurazone (NF) and human serum albumin (HSA) has been studied by fluorescence spectroscopy, FT-IR spectroscopy and molecular modeling methods. The results showed that the fluorescence of HSA was quenched by NF in a static quenching mechanism. Thermodynamic
Hamid R Moghimi et al.
International journal of pharmaceutics, 401(1-2), 47-50 (2010-09-22)
Microwaves (MW), a part of the electromagnetic spectrum at 0.3-300GHz, affect human body in different ways through its thermal and athermal effects, including fluidization of cell membranes and liquid crystalline systems. Due to presence of such structures in skin barrier
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