H-096

17α-Hydroxyprogesterone-d₈ (2,2,4,6,6,21,21,21-d₈)

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonyme(s) : 17alpha-Hydroxyprogesterone-D8 (2,2,4,6,6,21,21,21-D8) solution
• Formule empirique (notation de Hill): C₂₁H₂₂O₃D₈
• Numéro CAS: 850023-80-2
• Poids moléculaire : 338.51
• Numéro CE : 200-659-6
• Numéro MDL: MFCD03428149
• Code UNSPSC : 41116107
• ID de substance PubChem : 329815143
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 100 μg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing; clinical testing
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: [2H]C1=C2C([2H])([2H])C[C@@H]3[C@H](CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)C([2H])([2H])[2H])[C@@]2(C)CC([2H])([2H])C1=O
• InChI: 1S/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18,24H,4-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1/i1D3,4D2,6D2,12D
• Clé InChI: DBPWSSGDRRHUNT-LDLLURODSA-N

Description

Description générale

100 μg/mL in Methanol A stable labeled internal standard suitable for quantitation of 17α-Hydroxyprogesterone levels in LC-MS/MS testing assays for newborn screening or endocrinology.

Application

• Dried blood spot sampling of testosterone microdosing in healthy females: Demonstrates the application of 17 alpha-Hydroxyprogesterone-d8 in mass spectrometry standards to ensure precision in microdosing studies, highlighting its crucial role in developing therapeutic strategies for hormone balance (Desai et al., 2024).


• Calcium complexation by steroids involved in steroidogenesis: Features the use of 17 alpha-Hydroxyprogesterone-d8 in studying the interactions of steroids with minerals, providing a fundamental understanding of biochemical pathways crucial for hormone synthesis research (Siless and Cabrera, 2024).


• Multiplexed Serum Steroid Profiling Reveals Metabolic Signatures of Subtypes in Congenital Adrenal Hyperplasia: Utilizes 17 alpha-Hydroxyprogesterone-d8 as part of a comprehensive panel in mass spectrometry to differentiate subtypes of adrenal hyperplasia, showcasing its application in detailed biochemical profiling (Shim et al., 2023).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup