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Merck
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Key Documents

916471

Sigma-Aldrich

PhotoHA™ -LAP, methacrylated hyaluronic acid bioink kit, with LAP

Synonyme(s) :

3D Bioprinting, Bioink, HAMA, Hyaluronic acid

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About This Item

Code UNSPSC :
12352201
Nomenclature NACRES :
NA.23

Description

Methacrylated collagen:
Degree of methacrylation: ≥45-65%

Niveau de qualité

100

Stérilité

sterile; sterile-filtered

Température de stockage

−20°C

Application

PhotoHA™ -LAP bioink kit consists of methacrylated hyaluronic acid (HAMA) and LAP photoinitiator. Hyaluronic acid is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices, hyaluronic acid also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions. The photoinitiator consists of LAP to be formulated in 1X cell culture media or PBS, which allows blue light photocrosslinking of the printed structure at 405 nm. PhotoHA™ -LAP provides native-like 3D HA gels, and the final gel stiffness can be customized by changing HA concentrations and crosslinking.

Informations légales

PhotoHA is a trademark of Advanced BioMatrix, Inc.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Michelle T Poldervaart et al.
PloS one, 12(6), e0177628-e0177628 (2017-06-07)
In bone regenerative medicine there is a need for suitable bone substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit their applicability, especially with respect to 3D bioprinting. In this study, we modified the naturally occurring
Sudhir Khetan et al.
Cryobiology, 90, 83-88 (2019-08-06)
While significant progress has been made in directing the behavior of cells encapsulated within three-dimensional (3D) covalently crosslinked hydrogels, the capacity of these materials to support in situ cryopreservation of cells directly within the gels has not been assessed. Here

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