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917079

Sigma-Aldrich

PhotoHA™-IRG, methacrylated hyaluronic acid bioink kit, with Irgacure

Synonyme(s) :

3D Bioprinting, Bioink, HAMA, Hyaluronic acid

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About This Item

Code UNSPSC :
12352201
Nomenclature NACRES :
NA.23

Description

Methacrylated hyaluronic acid:
Degree of methacrylation: ≥ 45-65%

Niveau de qualité

100

Stérilité

sterile; sterile-filtered

Poids mol.

Mw 100-150  kDa

Composition

Product components :
Methacrylated hyaluronic acid (100 mg)
Irgacure photoinitiator (100 mg)

Température de stockage

−20°C

Application

PhotoHA™-IRG bioink kit consists of methacrylated hyaluronic acid (HAMA) and Irgacure photoinitiator. Hyaluronic acid is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices, hyaluronic acid also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions. The photoinitiator consists of Irgacure 2959 to be formulated in methanol (methanol not included), which allows UV crosslinking of the printed structure at 365 nm. PhotoHA™-IRG provides native-like 3D HA gels, and the final gel stiffness can be customized by changing HA concentrations and crosslinking.

Informations légales

PhotoHA is a trademark of Advanced BioMatrix, Inc.

Pictogrammes

Environment
GHS09

Mentions de danger

H411

Conseils de prudence

P273 - P391 - P501

Classification des risques

Aquatic Chronic 2

Code de la classe de stockage

11 - Combustible Solids

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Michelle T Poldervaart et al.
PloS one, 12(6), e0177628-e0177628 (2017-06-07)
In bone regenerative medicine there is a need for suitable bone substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit their applicability, especially with respect to 3D bioprinting. In this study, we modified the naturally occurring
Sudhir Khetan et al.
Cryobiology, 90, 83-88 (2019-08-06)
While significant progress has been made in directing the behavior of cells encapsulated within three-dimensional (3D) covalently crosslinked hydrogels, the capacity of these materials to support in situ cryopreservation of cells directly within the gels has not been assessed. Here

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