900618

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine

95%

• Synonyme(s) : Bromo diazirine alkyne, Probe building block
• Formule empirique (notation de Hill): C₁₁H₆BrF₃N₂
• Numéro CAS: 849607-28-9
• Poids moléculaire : 303.08
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: 95%
• Forme: solid
• Disponibilité: available only in USA
• Température de stockage: −20°C

Description

Application

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Autres remarques

Technology Spotlight: Trifunctional Probe Building Blocks
Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca²⁺ release from sarcoplasmic reticulum of skeletal muscle

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Danger
• Mentions de danger: H242
• Conseils de prudence: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Classification des risques: Self-react. C
• Code de la classe de stockage: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable