SAB4500756

Anti-APLF antibody produced in rabbit

affinity isolated antibody

• Sinónimos: APFL, C2orf13, Xip1, aprataxin and PNK-like factor
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 56 kDa
• species reactivity: human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: Q8IW19
• UniProt accession no.: Q8IW19
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... APLF(200558)

Descripción

General description

Aprataxin and PNKP-like factor (APLF) is also called as PALF and Xip1. It is located in the nucleus. APLF has a forkhead-associated (FHA) domain and two unique poly (ADP-ribose)-binding zinc finger (PBZ) domains in its C-terminal region. This gene is mapped to human chromosome 2p13.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human APLF.

Immunogen Range: 82-131

Biochem/physiol Actions

Aprataxin and PNKP-like factor (APLF) acts as a DNA repair factor. The forkhead-associated (FHA) domain of APLF helps to bind to the phosphorylated FHA domain binding motifs (FBMs) in XRCC1 and XRCC4. Other domains of APLF recruites APLF to sites of DNA damage.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable