MAK532

Nitric Oxide Synthase (NOS) Assay Kit

sufficient for 100 colorimetric tests

• Código UNSPSC: 12161503
• NACRES: NA.84

Propiedades

• Nivel de calidad: 100
• aplicaciones: pharmaceutical
• método de detección: colorimetric
• enfermedades relevantes: cardiovascular diseases; immunological diseases; aging/geriatric diseases; cancer
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Nitric oxide (NO) is a reactive radical that plays an important role in many key physiological functions. NO, an oxidation product of arginine by nitric oxide synthase (NOS), is involved in host defense and development, activation of regulatory proteins and direct covalent interaction with functional biomolecules.

Características y beneficios

• Linear detection range: 0.25 - 25 U/L

Idoneidad

The kit is suitable for the determination of nitric oxide synthase activity in biological samples, as well as for studying the effects of drugs on nitric oxide synthase activity.

Principio

The Nitric Oxide Synthase (NOS) Assay Kit nvolves two steps: a NOS reaction step during which NO is produced followed by an NO detection step. Since the NO generated by NOS is rapidly oxidized to nitrite and nitrate, the NO production is measured following reduction of nitrate to nitrite using an improved Griess method. The procedure is simple and the time required for sample pretreatment and assay is reduced to as short as 40 minutes.

Información de seguridad

• Pictogramas: GHS05,GHS07,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H290,H302,H314,H411
• Consejos de prudencia: P234 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A
• Código de clase de almacenamiento: 8A - Combustible corrosive hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3