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Merck

C6003

Sigma-Aldrich

Chlorophyllin sodium copper salt

commercial grade, powder

Sinónimos:

Chlorophyllin, coppered trisodium salt

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About This Item

Fórmula empírica (notación de Hill):
C34H31CuN4Na3O6
Número de CAS:
Peso molecular:
724.15
EC Number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Chlorophyllin sodium copper salt, commercial grade

grade

commercial grade

Quality Level

form

powder

color

black
green to very dark green

solubility

H2O: 100 mg/mL, dark green

application(s)

diagnostic assay manufacturing
hematology
histology

Storage temp.

2-8°C

SMILES string

[Na+].[Na+].[Na+].CCc1c(C)c2cc3c(C=C)c(C)c4cc5nc(C(CCC([O-])=O)C5C)c(CC([O-])=O)c6c(C([O-])=O)c(C)c(cc1n2)n6[Cu]n34

InChI

1S/C34H36N4O6.Cu.3Na/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23;;;;/h7,12-14,17,21H,1,8-11H2,2-6H3,(H5,35,36,37,38,39,40,41,42,43,44);;;;/q;+2;3*+1/p-5

Inchi Key

HWDGVJUIHRPKFR-UHFFFAOYSA-I

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Application

Chlorophyllin sodium copper salt has been used to study the effect of chlorophyllin against radiation-induced hematopoietic syndrome. It has been used to study the effect of chlorophyllin on the excretion of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its metabolites into the breast-milk of lactating rats.

Biochem/physiol Actions

Chlorophyllin is a water soluble derivative of chlorophyll. It has chemopreventive properties and forms a non-covalent complex with many mutagenic/carcinogenic molecules. The complex formation reduces absorption or allows excretion of the mutagenic/carcinogenic molecules. Chlorophyllin also exhibits antioxidant, antiapoptotic and immunostimulatory effects. It provides benefits, such as prevention of body odor and increased wound healing.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

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Distribution and metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in female rats and their pups at dietary doses.
Mauthe RJ, et al.
Carcinogenesis, 19, 919-924 (1998)
Zivile Luksiene et al.
Journal of photochemistry and photobiology. B, Biology, 105(1), 69-74 (2011-08-03)
The aim of this study was to evaluate efficiency of photosensitization as surface sanitation alternative using model systems when food pathogens, their spores and biofilms were attached to the food-related surface (polyolefine). In addition it was important to compare antibacterial
Wei Li et al.
Nanomedicine (London, England), 7(3), 383-392 (2012-03-06)
How to overcome insufficient drug release is an important issue in the drug-delivery system. Here, a novel temperature and UV dual-control poly(N-isopropylacrylamide [PNIPAM]-co-chlorophyllin) nanogel was prepared via the surfactant-free emulsion polymerization. The introduction of hydrophilic chlorophyllin to the PNIPAM chain
Maria Rosaria Grossi et al.
Toxicology letters, 214(3), 235-242 (2012-09-19)
Chlorophyllin (CHL), a water soluble derivative of chlorophyll has been shown to have both anticarcinogenic and antigenotoxic properties. We evaluated the protective effects of CHL (25μM in vitro, 4 and 100mg/kg. b.w.) on the clastogenic action of two model carcinogens
Jun Zhang et al.
The Analyst, 137(18), 4287-4294 (2012-08-02)
The human hepatoma 3B cell line was chosen as an experimental model for in vitro test of drug screening. The drugs included chlorophyllin and its derivatives such as fluo-chlorophyllin, sodium copper chlorophyllin, and sodium iron chlorophyllin. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT)

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