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A2754

Sigma-Aldrich

Adenosine 5′-diphosphate sodium salt

bacterial, ≥95% (HPLC)

Sinónimos:

ADP sodium salt, ADP

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About This Item

Fórmula empírica (notación de Hill):
C10H15N5O10P2
Número de CAS:
20398-34-9
Peso molecular:
427.20
Código UNSPSC:
41106305
eCl@ss:
32160414
ID de la sustancia en PubChem:
24890690
NACRES:
NA.51

origen biológico

bacterial

Nivel de calidad

300

Ensayo

≥95% (HPLC)

Formulario

powder

temp. de almacenamiento

−20°C

cadena SMILES

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Clave InChI

XTWYTFMLZFPYCI-KQYNXXCUSA-N

Información sobre el gen

human ... HSP90AA1(3320) , P2RY1(5028)

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Descripción general

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by FOF1-ATP synthases. ADP can also be obtained by adenylate monophosphate (AMP) reaction catalyzed by adenylate kinase. ADP is a platelet agonist that is secreted from platelet dense granules. It promotes platelet activation through its interaction with ADP receptors P2Y1 and P2Y12. Upon conversion of ADP to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Aplicación

Adenosine 5′-diphosphate sodium salt has been used:
  • as a positive control of platelet aggregation to analyze antiplatelet activity of purified disintegrin by aggregometery.
  • in the preparation of stock solution for a mito stress test.
  • as a positive control in flow cytometry analysis to study the effect of pentameric C-reactive protein (pCRP) and monomeric CRP (mCRP) on the CD62p (P-selectin) expression of platelets.
  • as a platelet agonist to stimulate platelet aggregation.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
0000428145
0000428145
0000426931
0000426931
0000426000

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