93659

L-Tryptophan

≥99.5% (NT), BioUltra

• Sinónimos: (S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid
• Fórmula empírica (notación de Hill): C₁₁H₁₂N₂O₂
• Número de CAS: 73-22-3
• Peso molecular: 204.23
• Beilstein: 86197
• Número CE: 200-795-6
• Número MDL: MFCD00064340
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 57653570
• NACRES: NA.26

Propiedades

• Nombre del producto: L-Tryptophan, BioUltra, ≥99.5% (NT)
• Línea del producto: BioUltra
• Nivel de calidad: 100
• Ensayo: ≥99.5% (NT)
• Formulario: powder or crystals
• actividad óptica: [α]20/D −31.5±1°, c = 1% in H₂O
• impurezas: insoluble matter, passes filter test
• residuo de ign.: ≤0.1%
• pérdida: ≤0.1% loss on drying, 20 °C (HV)
• color: white
• mp: 280-285 °C (dec.) (lit.)
• solubilidad: 0.5 M HCl: 0.1 g/mL at 20 °C, clear, colorless to faintly yellow
• trazas de anión: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• trazas de catión: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• Absorción: cut-off at 326 nm in 0.5 M HCl at 0.5 M
• aplicaciones: cell analysis
• cadena SMILES: N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
• InChI: 1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
• Clave InChI: QIVBCDIJIAJPQS-VIFPVBQESA-N

Descripción

Aplicación

L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines.[1] It has also been used as a test amino acid aerosol to study the variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols.[2]

Acciones bioquímicas o fisiológicas

Tryptophan (Trp) is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity.[3] Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.[4]

Otras notas

Amino acid precursor of serotonin and melatonin

In tryptophan-substituted Sephadex^® and Sepharose^™ for the improved chromatographic separation of cellulases[5]; As spacer in isotachophoresis of serum proteins[6]; Growth requirement of various microorganisms[7].

Información legal

Sephadex is a registered trademark of Cytiva

Sepharose is a trademark of Cytiva

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)