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Merck

04243

Sigma-Aldrich

Fosfato de potasio monobasic

meets analytical specification of Ph. Eur., NF, E340, anhydrous, 98-100.5% (calc. to the dried substance)

Sinónimos:

Dihidrógeno fosfato de potasio, Fosfato de monopatosio, prim.-Fosfato de potasio

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About This Item

Fórmula lineal:
KH2PO4
Número de CAS:
Peso molecular:
136.09
EC Number:
MDL number:
UNSPSC Code:
12161700
eCl@ss:
38070209
PubChem Substance ID:
NACRES:
NA.25

grade

anhydrous

Quality Level

assay

98-100.5% (calc. to the dried substance)

form

crystalline

quality

meets analytical specification of Ph. Eur., NF, E340

impurities

org. volatile impurities, complies (GC)
residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.04% KMnO4 red. matter (as O)
≤0.2% in water insoluble matters

loss

≤1% loss on drying, 130 °C

pH

4.2-4.5 (20 °C, 5%)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

mp

252.6 °C (lit.)

solubility

H2O: soluble 4.5 parts
alcohol: insoluble

density

2.338 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤10 mg/kg
fluoride (F-): ≤10 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤20 mg/kg
Fe: ≤10 mg/kg
Hg: ≤1 mg/kg
Na: ≤1000 mg/kg
Pb: ≤4 mg/kg
Zn: ≤20 mg/kg

suitability

complies for appearance of solution

SMILES string

[K+].OP(O)([O-])=O

InChI

1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

InChI key

GNSKLFRGEWLPPA-UHFFFAOYSA-M

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Application

Potassium phosphate monobasic was used for separating tobacco protein by using aqueous two-phase extraction.

Biochem/physiol Actions

Potassium phosphate monobasic also referred to as monopotassium phosphate or potassium dihydrogen phosphate is a soluble salt of potassium that serves as a buffering agent. It enhances the solubility of calcium and phosphorus in amino acid plus dextrose solutions and hence assists in improving the mineral balance of parenterally fed low birth weight infants.

Preparation Note

Potassium phosphate monobasic dissolves in 4.5 (approx.) parts of water to yield a solution. It is practically insoluble in alcohol.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Deepa Balasubramaniam et al.
Journal of chromatography. A, 989(1), 119-129 (2003-03-19)
Tobacco has long been considered as a host to produce large quantity of high-valued recombinant proteins. However, dealing with large quantities of biomass is a challenge for downstream processing. Aqueous two-phase extraction (ATPE) has been widely used in purifying proteins
P Chessex et al.
The Journal of pediatrics, 116(5), 765-772 (1990-05-01)
Because the monobasic potassium phosphate salt (monobasic) improves the solubility of calcium and phosphorus in amino acid plus dextrose solutions, compared with the current mixtures of monobasic plus dibasic salts (dibasic), we tested the bioavailability and clinical effects of monobasic
Jian Zheng et al.
PloS one, 9(4), e94712-e94712 (2014-04-15)
The human organic anion transporting polypeptide 1A2 (OATP1A2) is an important membrane protein that mediates the cellular influx of various substances including drugs. Previous studies have shown that PDZ-domain containing proteins, especially PDZK1 and NHERF1, regulate the function of related
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Disease models & mechanisms, 7(6), 635-648 (2014-05-09)
A point mutation in the Drosophila gene that codes for the major adult isoform of adenine nuclear translocase (ANT) represents a model for human diseases that are associated with ANT insufficiency [stress-sensitive B(1) (sesB(1))]. We characterized the organismal, bioenergetic and
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Journal of the American College of Cardiology, 64(19), 2013-2023 (2014-12-03)
Obstructive sleep apnea (OSA) importantly contributes to the occurrence of atrial fibrillation (AF) in humans, but the mechanisms are poorly understood. Experimental research has provided insights into AF promotion by acute OSA episodes. However, patients with OSA usually have frequent nocturnal episodes

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