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PHR1963

Supelco

(+)-Catechin

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

(+)-Catechin, (+)-Cyanidanol, D-Catechin

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50 MG
$261.000

$261.000

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50 MG
$261.000

About This Item

Fórmula empírica (notación de Hill):
C15H14O6
Número de CAS:
154-23-4
Peso molecular:
290.27
Número MDL:
MFCD00075649
Código UNSPSC:
41116107
NACRES:
NA.24

$261.000

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grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

300

Agency

traceable to USP 1096790

familia API

catechins

CofA

current certificate can be downloaded

envase

pkg of 50 mg

aplicaciones

pharmaceutical

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s1

Clave InChI

PFTAWBLQPZVEMU-DZGCQCFKSA-N

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Descripción general

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

(+)-Catechin is a flavan-3-ol, that belongs to the family of polyphenolic flavonoids, called catechins. Found in green tea, it shows many health benefits, such as anti-oxidant, anti-inflammatory, anti-proliferative, and anti-platelet activity.

Aplicación

This pharmaceutical secondary standard can also be used as follows:

  • Development of an ultra-high performance liquid chromatography-triple-quadrupole tandem mass spectrometry (UHPLC-MS-MS) method for the simultaneous determination of eight catechins and four theaflavins in three types of tea samples
  • Separation and estimation of six tea catechins and caffeine by an UHPLC method coupled to a UV detector from green tea samples
  • Simultaneous analysis of five naturally occurring catechins by an isocratic HPLC method
  • Infrared-assisted extraction (IRAE) followed by HPLC separation and quantification of catechin, epicatechin, and procyanidin B2 in grape seed samples[1]
  • Analysis of caffeine and catechins from green tea leaves by pressurized liquid extraction (PLE) using ethyl lactate, water, and ethyl lactate + water mixtures[2]

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC2624 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Pressurized liquid extraction of caffeine and catechins from green tea leaves using ethyl lactate, water and ethyl lactate+ water mixtures
Bermejo DV, et al.
Food and Bioproducts Processing, 96, 106-112 (2015)
Study on infrared-assisted extraction coupled with high performance liquid chromatography (HPLC) for determination of catechin, epicatechin, and procyanidin B2 in grape seeds
Cai Y, et al.
Food Chemistry, 127, 1872-1877 (2011)
Giftson J Senapathy et al.
Molecules (Basel, Switzerland), 25(21) (2020-10-28)
Worldwide, lung cancer remains one of the leading cancers with increasing mortality rates. Though chemotherapy for lung cancer is effective, it is always accompanied by unavoidable and grave side effects. Photodynamic therapy (PDT), using novel photosensitizers, is an advanced treatment

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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