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A0420000

Aminocaproic acid

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

6-Aminocaproic acid, ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA

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About This Item

Fórmula lineal:
H2N(CH2)5CO2H
Número de CAS:
60-32-2
Peso molecular:
131.17
Beilstein/REAXYS Number:
906872
MDL number:
MFCD00008238
UNSPSC Code:
41116107
PubChem Substance ID:
329770612
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

aminocaproic acid

manufacturer/tradename

EDQM

mp

207-209 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

InChI key

SLXKOJJOQWFEFD-UHFFFAOYSA-N

Gene Information

human ... PLAT(5327) , PLG(5340)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aminocaproic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Allergic contact dermatitis due to epsilon-aminocaproic acid: a case report and mini-review of the published work.
Yuriko Yamamoto et al.
The Journal of dermatology, 40(4), 301-303 (2013-02-13)
G Manjunath et al.
Clinical nephrology, 58(1), 63-67 (2002-07-27)
Epsilon-aminocaproic acid (EACA) is a potent anti-fibrinolytic agent that is used in the treatment of excessive bleeding resulting from a systemic fibrinolytic state. It can also be used to treat hematuria through its action on decreasing urinary fibrinolysis. A broad
Blood-sparing drugs: aprotinin, tranexamic acid, and epsilon-aminocaproic acid.
D Royston
International anesthesiology clinics, 33(1), 155-179 (1995-01-01)
Are antifibrinolytic agents effective in the treatment of aneurysmal subarachnoid hemorrhage?
Travis R Eastin et al.
Annals of emergency medicine, 64(6), 658-659 (2014-06-24)
O N Lucas et al.
Oral surgery, oral medicine, and oral pathology, 51(2), 115-120 (1981-02-01)
On the basis of our review of the literature, it can be concluded that the advantages of E-A.C.A. include (1) safe execution of oral surgical procedures in persons with hemophilia of varying degrees of severity, (2) decrease or total elimination
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