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46165

Dexametasona

Name: Dexametasona
Brand: SIAL
Price: 113000 CLP

VETRANAL^®, analytical standard

Sinónimos:

(11β,16α)-9-Fluoro-11,17,21-trihidroxi-16-metilpregna-1,4-dieno-3,20-diona, 9α-Fluoro-16α-metil-11β,17α,21-trihidroxi-1,4-pregnadieno-3,20-diona, 9α-fluoro-16α-metilprednisolona, Prednisolona F

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Talla/SKU	Disponibilidad	Precio
250 mg	Comprobar disponibilidad del carrito	$113.000

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₂₂H₂₉FO₅

Número CAS:

50-02-2

Peso molecular:

392.46

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329757092

EC Number:

200-003-9

Beilstein/REAXYS Number:

2066651

MDL number:

MFCD00064136

$113.000

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Servicio técnico

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Propiedades

grade

analytical standard

Quality Segment

100

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

mp

262-264 °C (lit.)

application(s)

clinical

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

InChI key

UREBDLICKHMUKA-CXSFZGCWSA-N

Gene Information

human ... NR3C1(2908)

Descripción

General description

Dexamethasone is a synthetic glucocorticoid and cortisol analogue. It is used in the suppression of adrenocorticotropic hormone (ACTH) and cortisol production in normal subjects.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Dexamethasone may be used as a reference standard in the determination of dexamethasone in biological samples using high-performance liquid chromatography (HPLC).

Biochem/physiol Actions

Glucocorticoide antiinflamatorio

Glucocorticoide antiinflamatorio. Regula la supervivencia, el crecimiento y la diferenciación de las células T. Inhibe la inducción de la óxido nítrico sintasa.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo	PHR1526	31375	D8893
Supelco 46165 Dexametasona	Supelco PHR1526 Dexametasona	Sigma-Aldrich 31375 Dexametasona	Sigma-Aldrich D8893 Dexametasona
description VETRANAL^®, analytical standard	description Pharmaceutical Secondary Standard; Certified Reference Material	description tested according to Ph. Eur.	description powder, γ-irradiated, BioXtra, suitable for cell culture, ≥80% (HPLC)
grade analytical standard	grade certified reference material, pharmaceutical secondary standard	grade -	grade -
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) gas chromatography (GC): suitable, HPLC: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable
application(s) clinical	application(s) pharmaceutical (small molecule)	application(s) research use (small molecule)	application(s) -
format neat	format neat	format -	format -
Gene Information human ... NR3C1(2908)	Gene Information human ... NR3C1(2908)	Gene Information human ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908) mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926) rat ... Ar(24208), Nr3c1(24413), Tnf(24835)	Gene Information human ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908) mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926) rat ... Ar(24208), Nr3c1(24413), Tnf(24835)
storage temp. 2-8°C	storage temp. 2-30°C	storage temp. -	storage temp. 2-8°C

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Pictogramas

GHS08

Palabra de advertencia

Danger

Códigos de peligro

H360FD

Indicaciones de precaución

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number

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