None of the methylene blue products are considered API or suitable for use in manufacturing medical devices. They are offered for Research Use Only or for In Vitro Diagnostic Testing. Methylene blue is offered as methylene blue chloride and as a methylene blue zinc chloride double salt, each with slightly different formulas and molecular weights. Methylene blue chloride is the form of the dye used in most biological staining applications and medicinal uses. It is recommended to source methylene blue from approved pharmaceutical suppliers, especially considering the availability of methylene blue USP grade.
28514
Methylene Blue hydrate
≥95% (calc. to the dried substance)
Sinónimos:
Basic Blue 9 monohydrate ; Methylene Blue (hydrate)
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100 G
$148.000
1 KG
$971.000
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100 G
$148.000
1 KG
$971.000
About This Item
Fórmula empírica (notación de Hill):
C16H18ClN3S · xH2O
Número de CAS:
Peso molecular:
319.85 (anhydrous basis)
Beilstein:
3599847
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
NACRES:
MA.02
Productos recomendados
Nivel de calidad
Ensayo
≥95% (calc. to the dried substance)
Formulario
powder
impurezas
≤1% insoluble in ethanol
pérdida
≤22% loss on drying, 105 °C
color
very dark green
solubilidad
ethanol: insoluble ≤1%
aplicaciones
diagnostic assay manufacturing
hematology
histology
temp. de almacenamiento
room temp
cadena SMILES
O.[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C
InChI
1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
Clave InChI
WQVSELLRAGBDLX-UHFFFAOYSA-M
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Descripción general
Methylene blue is bis(dimethylamino)phenothiazine hydrochloride (tetramethylthionine),
C16H18N3SCl. It is a major basic histological dye in pharmacology and microbiology. This heterocyclic aromatic chemical appears as a dark green solid powder, changing to blue in an aqueous solution. Methylene blue is tested for histological and and bacteriological staining, and as a constituent of Wright’s blood stain.
C16H18N3SCl. It is a major basic histological dye in pharmacology and microbiology. This heterocyclic aromatic chemical appears as a dark green solid powder, changing to blue in an aqueous solution. Methylene blue is tested for histological and and bacteriological staining, and as a constituent of Wright’s blood stain.
Aplicación
Methylene blue is widely used in several routine staining applications including Mallory’s phloxine-methylene blue on paraffin sections of tissue fixed in Zenker’s fluid for nuclear staining and bacterial staining in milk. It is also suitable for manufacturing the polychrome methylene blue used in the preparation of Romanowsky stains.Methylene Blue hydrate has also been used:
- in the preparation of methylene blue (MB) solution
- to stain zymograms -to label the injection site in the tissue slices
- to pre-treat mice via oral gavage to study its effects on noise-induced hearing loss
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 4 Oral
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Gloves
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Are any of the methylene blue products considered API or suitable for use in manufacturing medical devices? The products offered for sale are for Research Use Only or for In Vitro Diagnostic Testing? Additionally, what are the differences between methylene blue chloride and methylene blue zinc chloride double salt offered?
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