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371725

Sigma-Aldrich

GPR43 (FFA2) Agonist

The GPR43 (FFA2) Agonist controls the biological activity of GPR43. This small molecule/inhibitor is primarily used for Biochemicals applications.

Sinónimos:

GPR43 (FFA2) Agonist, (S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide

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About This Item

Fórmula empírica (notación de Hill):
C21H21ClN2OS
Número de CAS:
1208552-99-1
Peso molecular:
384.92
UNSPSC Code:
51111800
NACRES:
NA.77

Quality Level

100

assay

>98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

DMSO: 50 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

A phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50 = 0.7 µM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Wang, Y., et al. 2009. Bioorg. Med. Chem. Lett.20, 493.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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