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264101

Deoxycholic Acid sodium

Name: Deoxycholic Acid sodium
Brand: MM

An ionic detergent for the solubilization of membrane-bound proteins.

Sinónimos:

Sodium deoxycholate, 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

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Fórmula empírica (notación de Hill):

C₂₄H₃₉NaO₄

Número CAS:

302-95-4

Peso molecular:

414.55

NACRES:

NA.21

UNSPSC Code:

12161902

Beilstein/REAXYS Number:

3581950

MDL number:

MFCD00064139

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Propiedades

Quality Segment

100

description

Merck USA index - 14, 2899

assay

≥96% (TLC)

form

powder

mol wt

micellar avg mol wt 1200-5000, micellar wt 1700-4200

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

aggregation number

3-12, 4 - 10

color

white to off-white

pKa

6.2

CMC

2-6 mM (20-25°C), 4 - 8 mM

solubility

H₂O: 2%, clear, colorless

cation traces

heavy metals: ≤20.0 ppm

HLB

shipped in

ambient

storage temp.

15-25°C

SMILES string

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

Descripción

General description

An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).

Other Notes

Pai, R., et al. 2004. Mol. Biol. Cell15 2156.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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Este artículo	S1827	30970	D6750
Millipore 264101 Deoxycholic Acid sodium	SAFC S1827 Sodium deoxycholate	Sigma-Aldrich 30970 Sodium deoxycholate	Sigma-Aldrich D6750 Sodium deoxycholate
description An ionic detergent for the solubilization of membrane-bound proteins.	description -	description BioXtra, ≥98.0% (dry matter, NT)	description ≥97% (titration)
form powder	form powder	form powder	form powder
assay ≥96% (TLC)	assay ≥98% (HPLC)	assay ≥98.0% (dry matter, NT)	assay ≥97% (titration)
aggregation number 4 - 10, 3-12	aggregation number 3-12	aggregation number 3-12	aggregation number 3-12
storage temp. 15-25°C	storage temp. -	storage temp. -	storage temp. room temp
solubility H₂O: 2%, clear, colorless	solubility -	solubility water: soluble 1 gm in 10 ml, clear, colorless to very faintly yellow	solubility -
cation traces heavy metals: ≤20.0 ppm	cation traces -	cation traces Ca: ≤500 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cr: ≤5 mg/kg, Mg: ≤10 mg/kg, Mn: ≤5 mg/kg, Pb: ≤10 mg/kg, Co: ≤5 mg/kg, Cd: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤10 mg/kg	cation traces -

Pictogramas

GHS07

Palabra de advertencia

Warning

Códigos de peligro

H302

Indicaciones de precaución

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

WGK

WGK 1

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)