14-927-M

PAK1 Protein, active, 10 µg

Active, N-terminal FLAG-tagged, recombinant, human PAK1, amino acids 150-end. For use in Kinase Assays.

• UNSPSC Code: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

Propiedades

• biological source: human
• Quality Level: 100
• recombinant: expressed in baculovirus infected Sf21 cells
• mol wt: M_w 46 kDa
• manufacturer/tradename: Upstate^®
• technique(s): activity assay: suitable (kinase)
• NCBI accession no.: NM_002576
• UniProt accession no.: Q13153

Descripción

General description

Product Source: N-terminal FLAG-tagged, recombinant, human PAK1 amino acids 150-end, expressed by baculovirus in Sf21 insect cells.

This protein is a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Biochem/physiol Actions

Protein Target: PAK1

Packaging

Also available in 10μg size as catalog # 14-927 and in 250 μg as catalog # 14-927M.

Quality

Routinely evaluated by phosphorylation of peptide RRRLSFAEPG.

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable