C-243

C-Peptide solution

100 μg/mL (Protease-free 1x PBS), certified reference material, ampule of 0.5 mL, Cerilliant^®

• Fórmula empírica (notación de Hill): C₁₂₉H₂₁₁N₃₅O₄₈
• Número de CAS: 33017-11-7
• Peso molecular: 3020.26
• MDL number: MFCD00076295
• UNSPSC Code: 12352209
• NACRES: NA.24

Propiedades

• grade: certified reference material
• Quality Level: 300
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 0.5 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL (Protease-free 1x PBS)
• format: single component solution
• storage temp.: −20°C
• SMILES string: N2([C@@H](CCC2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)CN
• InChI: 1S/C129H211N35O48/c1-58(2)42-77(155-113(195)74(31-39-102(184)185)151-127(209)105(65(15)16)162-114(196)71(25-32-88(131)167)145-95(174)54-141-126(208)104(64(13)14)161-115(197)72(26-33-89(132)168)150-118(200)80(45-61(7)8)156-121(203)83(48-103(186)187)159-112(194)73(30-38-101(182)183)148-107(189)67(18)143-109(191)69(130)24-36-99(178)179)111(193)138-50-93(172)135-49-92(171)136-55-98(177)163-40-20-22-86(163)124(206)140-51-94(173)142-66(17)106(188)137-52-96(175)146-84(56-165)122(204)157-81(46-62(9)10)119(201)152-75(27-34-90(133)169)128(210)164-41-21-23-87(164)125(207)160-78(43-59(3)4)116(198)144-68(19)108(190)154-79(44-60(5)6)117(199)149-70(29-37-100(180)181)110(192)139-53-97(176)147-85(57-166)123(205)158-82(47-63(11)12)120(202)153-76(129(211)212)28-35-91(134)170/h58-87,104-105,165-166H,20-57,130H2,1-19H3,(H2,131,167)(H2,132,168)(H2,133,169)(H2,134,170)(H,135,172)(H,136,171)(H,137,188)(H,138,193)(H,139,192)(H,140,206)(H,141,208)(H,142,173)(H,143,191)(H,144,198)(H,145,174)(H,146,175)(H,147,176)(H,148,189)(H,149,199)(H,150,200)(H,151,209)(H,152,201)(H,153,202)(H,154,190)(H,155,195)(H,156,203)(H,157,204)(H,158,205)(H,159,194)(H,160,207)(H,161,197)(H,162,196)(H,178,179)(H,180,181)(H,182,183)(H,184,185)(H,186,187)(H,211,212)/t66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,104-,105-/m0/s1
• InChI key: VOUAQYXWVJDEQY-QENPJCQMSA-N

Descripción

General description

C-peptide, also known as the connecting peptide, is a 31-amino-acid polypeptide connecting insulin′s A-chain to its B-chain in the proinsulin molecule. Measurement of C-peptide blood serum levels can be used to distinguish between diabetes or hypoglycemia conditions with similar clinical features. This certified Snap-N-Spike^® solution of the fully-intact c-peptide protein is suitable for use as starting material in calibrators and controls in LC-MS/MS c-peptide testing methods.

This certified reference material (CRM) is a primary standard. It is traceable to the SI and higher order standards from National Institute of Standards and Technology (NIST) through an unbroken chain of comparisons. This C-Peptide (human) acetate salt is available as a solution of a pure substance in phosphate buffered saline with a pH of 7.4.

Application

C-Peptide solution is suitable for analytical and R&D applications for in vitro identification, calibration, and quantification.

Features and Benefits

• The total C-Peptide content is quantitatively determined using amino acid analysis (AAA) and HPLC/UV/MS, including unmodified, isomers, and pyroglu species, establishing traceability through the calibration of certification techniques.
• Each raw material used in the preparation of this standard has undergone thorough identification and characterization using multiple analytical techniques.
• The gravimetric preparation of this standard follows ISO 17025 requirements, utilizing qualified and calibrated balances.
• Fill volume conformity is ensured throughout the dispensing process by gravimetric verification using qualified and calibrated balances.
• Long-term stability under freezer storage (-10 °C to -25 °C) conditions has been evaluated.

Preparation Note

• Thaw the product in the refrigerator or at room temperature.
• Ensure thorough mixing before use.
• Avoid refreezing the product once it has thawed.
• For accurate results, quantitatively transfer the desired volume using established good laboratory practices.
• Use the transferred product to spike into the matrix or dilute it to achieve the desired concentration.

Other Notes

This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. For comprehensive details regarding the nature of any hazards and recommended precautions, kindly refer to the safety data sheet.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable