Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

860592P

Avanti

24:0 SM

Avanti Research™ - A Croda Brand 860592P, powder

Sinónimos:

N-lignoceroyl-D-erythro-sphingosylphosphorylcholine

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización

Seleccione un Tamaño

5 MG
$378.000

$378.000

Fecha estimada de envío22 de abril de 2025

Solicitar un pedido a granel
Todas las fotos(1)

Seleccione un Tamaño

Cambiar Vistas
5 MG
$378.000

About This Item

Fórmula empírica (notación de Hill):
C47H95N2O6P
Número de CAS:
60037-60-7
Peso molecular:
815.24
MDL number:
MFCD22416890
UNSPSC Code:
12352211
NACRES:
NA.25

$378.000

Fecha estimada de envío22 de abril de 2025

Solicitar un pedido a granel

form

powder

packaging

pkg of 1 × 10 mg (860592P-10mg)
pkg of 1 × 5 mg (860592P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860592P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C47H95N2O6P/c1-6-8-10-12-14-16-18-20-21-22-23-24-25-26-27-29-31-33-35-37-39-41-47(51)48-45(44-55-56(52,53)54-43-42-49(3,4)5)46(50)40-38-36-34-32-30-28-19-17-15-13-11-9-7-2/h38,40,45-46,50H,6-37,39,41-44H2,1-5H3,(H-,48,51,52,53)/b40-38+/t45-,46+/m0/s1

InChI key

QEDPUVGSSDPBMD-XTAIVQBESA-N

General description

d-erythro (2S, 3R) sphingomyelin (C24:0-SM) is a synthetic sphingomyelin[1] with acyl chain comprising 24 carbon atom. It is produced by the acylation of D-erythro-sphingosylphosphorylcholine.[2] Sphingomyelin is a key constituent of mammalian cell plasma membranes. It is mainly found at high concentrations in the myelin sheaths of nerve cells, in brain, eye lens and red blood cells. SM have asymmetric molecular structure and high hydrogen-bonding capacity.[1]

Application

24:0 sphingomyelin (SM) is suitable to study its thermotropic and mechanical properties by using differential scanning calorimetry.[1] It is also suitable for use as a lipid standard in ultrafast liquid chromatography−tandem mass spectrometry.[3]

Biochem/physiol Actions

Sphingomyelin (SM) are involved in the formation of functional domains in the membrane bilayer. It also acts as a precursor for sphingolipid signaling molecules including, ceramides and other sphingolipid metabolites.[1]

Packaging

5 mL Amber Glass Screw Cap Vial (860592P-10mg)
5 mL Amber Glass Screw Cap Vial (860592P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Very-long-chain fatty acid sphingomyelin in nuclear lipid microdomains of hepatocytes and hepatoma cells: can the exchange from C24: 0 to C16: 0 affect signal proteins and vitamin D receptor?
Lazzarini A, et al.
Molecular Biology of the Cell, 26(13), 2418-2425 (2015)
Mechanical properties of milk sphingomyelin bilayer membranes in the gel phase: Effects of naturally complex heterogeneity, saturation and acyl chain length investigated on liposomes using AFM
Et-Thakafy O, et al.
Chemistry and Physics of Lipids, 210, 47-59 (2018)
Phase transitions of highly asymmetric chain-length N-lignocerylsphingomyelin (C24: 0-SM) bilayer
Ohtaka H, et al.
Journal of Thermal Analysis and Calorimetry, 113(3), 1593-1602 (2013)
Elisabetta Albi et al.
International journal of molecular sciences, 15(7), 11555-11565 (2014-07-01)
Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico