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810192C

Avanti

16:0-06:0 NBD PS

Avanti Research™ - A Croda Brand 810192C

Sinónimos:

1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

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About This Item

Fórmula empírica (notación de Hill):
C34H59N6O13P
Número de CAS:
384833-06-1
Peso molecular:
790.84
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810192C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810192C

concentration

1 mg/mL (810192C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylserine (PS) is a minor phospholipid present in the membranes of prokaryotic and eukaryotic cells. It comprises 2-10% of total phospholipids, enriched in brain. NBD PS is labelled at the headgroup of PS with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD).

Application

16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) is suitable to measure the enzyme specificity of lipoteichoic acid (LTA) synthase (LtaS) and in liposomes to determine the role of phospholipid scramblase 1 (PLSCR1) in phospholipid scrambling.

Biochem/physiol Actions

Phosphatidylserine (PS) contributes to the clearance of apoptotic cells. It is involved in maintaining the nerve cell membrane and myelin sheath. It is associated with cognitive disability in Alzheimer′s disease.

Packaging

5 mL Amber Glass Screw Cap Vial (810192C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Nobuto Arashiki et al.
Biochemistry, 55(25), 3504-3513 (2016-06-09)
An asymmetric distribution of phospholipids in the membrane bilayer is inseparable from physiological functions, including shape preservation and survival of erythrocytes, and by implication other cells. Aminophospholipids, notably phosphatidylserine (PS), are confined to the inner leaflet of the erythrocyte membrane
Jean E Vance et al.
Progress in lipid research, 44(4), 207-234 (2005-06-28)
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and enzymes that are involved in PS biosynthesis in bacteria, yeast, plants and mammalian cells and discuss
Maria Mercedes Palomino et al.
Microbiology (Reading, England), 159(Pt 11), 2416-2426 (2013-09-10)
The probiotic Gram-positive bacterium Lactobacillus casei BL23 is naturally confronted with salt-stress habitats. It has been previously reported that growth in high-salt medium, containing 0.8 M NaCl, leads to modifications in the cell envelope of this bacterium. In this study
Soumi Mukherjee et al.
Chemistry and physics of lipids, 127(1), 91-101 (2004-01-07)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. NBD-labeled lipids have previously been used to monitor the organization and
Mirka E Wörmann et al.
Molecular microbiology, 79(3), 566-583 (2011-01-25)
Lipoteichoic acid (LTA) is an important cell wall polymer in Gram-positive bacteria. The enzyme responsible for polyglycerolphosphate LTA synthesis is LtaS, first described in Staphylococcus aureus. Four LtaS orthologues, LtaS(BS) , YfnI, YqgS and YvgJ, are present in Bacillus subtilis.
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