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810152P

Avanti

14:0-12:0 NBD PE

Avanti Research - A Croda Brand 810152P, powder

Sinónimos:

1-myristoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine

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1 MG
$209.000

$209.000


Fecha estimada de envío14 de abril de 2025


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1 MG
$209.000

About This Item

Fórmula empírica (notación de Hill):
C37H64N5O11P
Número de CAS:
Peso molecular:
785.90
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

$209.000


Fecha estimada de envío14 de abril de 2025


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assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810152P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810152P

shipped in

dry ice

storage temp.

−20°C

Categorías relacionadas

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labeled lipid localized to the membrane interface.[1][2] The molecule contains NBD as a fluorophore moiety linked to the headgroup of phosphatidylethanolamine.[2] Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid. It is mostly enriched in brain.[3]

Biochem/physiol Actions

Phosphoethanolamine present in cardiac myocytes plays a vital role in the prevention of cell damage after ischemia.[3] N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) supports the sensing of the Red edge excitation shift (REES) phenomenon with the unique motional and dielectric properties it possesses.[1]

Packaging

5 mL Amber Glass Screw Cap Vial (810152P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


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Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
S C Lopes et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1152-1161 (2019-03-07)
Mitochondrial membranes are pointed out as the site of cardiotoxic action of local anaesthetics. Its three main phospholipids components are phosphatidylcholine, phosphatidylethanolamine and cardiolipin. Cardiolipins, in eukaryotes, are only found in mitochondria and are essential for the maintenance of its
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in

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