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930024

Sigma-Aldrich

Hyaluronic acid adipic dihydrazide (HA-ADH)

Sinónimos:

HA-ADH

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About This Item

Fórmula lineal:
(C20H33N5O12)n
Código UNSPSC:
12352125
NACRES:
NA.23

Formulario

solid (Chunks)

Nivel de calidad

100

color

white to off-white

aplicaciones

3D bioprinting

temp. de almacenamiento

2-8°C

Categorías relacionadas

Descripción general

Adipic acid dihydrazide is commonly used as a functional group to allow for HA cross-linking to polymers containing aldehyde groups or that are aldehyde-functionalized, like HA-aldehyde or PEG-aldehyde. These biomaterials are attractive for their tunable properties and low cytotoxicity.
Degree of functionalization (50-80%)

Aplicación

Hyaluronic acid (HA) is a ubiquitous extracellular matrix component, which makes it attractive for use in medical applications for it′s biocompatibility and low immunogenicity. HA-based polymers are used to make hydrogels for a wide variety of applications from tissue engineering and regeneration to drug delivery and bioinks for 3D bioprinting. To make hydrogels, HA has to be derivatized with groups that can cross-link to to other functionalized polymers.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCS0397

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Artículos

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

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