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162663

Sigma-Aldrich

DL-2-Aminobutyric acid

99%, for peptide synthesis, ReagentPlus®

Sinónimos:

AABA, Homoalanine, alpha-amino-n-butyric acid

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About This Item

Fórmula lineal:
C2H5CH(NH2)CO2H
Número de CAS:
2835-81-6
Peso molecular:
103.12
Beilstein/REAXYS Number:
635889
EC Number:
220-616-5
MDL number:
MFCD00008093
UNSPSC Code:
12352116
PubChem Substance ID:
24849999
NACRES:
NA.22

product name

DL-2-Aminobutyric acid, ReagentPlus®, 99%

Quality Level

200

product line

ReagentPlus®

assay

99%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

291 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CCC(N)C(O)=O

InChI

1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)

InChI key

QWCKQJZIFLGMSD-UHFFFAOYSA-N

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General description

DL-2-Aminobutyric acid also known as α-aminobutyric acid, is commonly used in solution-phase peptide synthesis.

Application

DL-2-Aminobutyric acid can be used to synthesize 2-(2,5-dioxopyrrolidin-1-yl) butanoic acid.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Design, synthesis, and anticonvulsant activity of new hybrid compounds derived from 2-(2, 5-dioxopyrrolidin-1-yl) propanamides and 2-(2, 5-dioxopyrrolidin-1-yl) butanamides
Journal of Medicinal Chemistry, 58, 5274-5286 (2015)
Ryan J Martinie et al.
Journal of the American Chemical Society, 137(21), 6912-6919 (2015-05-13)
The iron(II)- and 2-(oxo)glutarate-dependent (Fe/2OG) oxygenases catalyze an array of challenging transformations, but how individual members of the enzyme family direct different outcomes is poorly understood. The Fe/2OG halogenase, SyrB2, chlorinates C4 of its native substrate, l-threonine appended to the
Danica P Galonić et al.
Nature chemical biology, 3(2), 113-116 (2007-01-16)
Enzymatic incorporation of a halogen atom is a common feature in the biosyntheses of more than 4,500 natural products. Halogenation of unactivated carbon centers in the biosyntheses of several compounds of nonribosomal peptide origin is carried out by a class
Young-Man Seo et al.
Organic & biomolecular chemistry, 10(12), 2482-2485 (2012-02-22)
A deracemization method was developed to generate optically pure L-homoalanine from racemic homoalanine using D-amino acid oxidase and ω-transaminase. A whole cell reaction using a biphasic system converted 500 mM racemic homoalanine to 485 mM L-homoalanine (>99% ee).
Christian Rausch et al.
Proteins, 81(5), 774-787 (2012-12-15)
Apart from their crucial role in metabolism, pyridoxal 5'-phosphate (PLP)-dependent aminotransferases (ATs) constitute a class of enzymes with increasing application in industrial biotechnology. To provide better insight into the structure-function relationships of ATs with biotechnological potential we performed a fundamental
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