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Key Documents

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153516

Sigma-Aldrich

Lactobionic acid

97% (TLC)

Sinónimos:

4-O-β-D-Galactopyranosyl-D-gluconic acid

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About This Item

Fórmula empírica (notación de Hill):
C12H22O12
Número de CAS:
96-82-2
Peso molecular:
358.30
Beilstein/REAXYS Number:
95054
EC Number:
202-538-3
MDL number:
MFCD00078147
UNSPSC Code:
12352201
PubChem Substance ID:
329750828
NACRES:
NA.25

biological source

synthetic

assay

97% (TLC)

form

powder or crystals

optical activity

[α]20/D +25°, c = 10 in H2O

color

white

mp

113-118 °C (lit.)

solubility

5%, clear, colorless

storage temp.

room temp

SMILES string

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(O)=O

InChI

1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1

InChI key

JYTUSYBCFIZPBE-AMTLMPIISA-N

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Application

Lactobionic acid, an α-hydroxyacid (AHA) with antioxidation activity, is used in the development of cosmeceuticals for skin. Lactobionic acid is used in the development of targeting drug delivery systems, such as microcapsules.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

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Barbara A Green et al.
Clinics in dermatology, 27(5), 495-501 (2009-08-22)
The hydroxyacids are represented by the alpha-hydroxyacids, beta-hydroxyacids, polyhydroxy acids, and bionic acids. Together, these ingredients form a class of compounds with unparalleled benefits to the skin and unprecedented usage in the cosmeceutical market in cosmetic and therapeutic formulations alike.
Xuejiao Zhang et al.
Journal of pharmaceutical sciences, 102(1), 145-153 (2012-11-08)
Mixed copolymer nanoparticles (NPs) self-assembled from β-cyclodextrin-grafted hyperbranched polyglycerol (HPG-g-CD) and lactobionic acid (LA)-grafted hyperbranched polyglycerol (HPG-g-LA) were applied as carriers for a hydrophobic antitumor drug, paclitaxel (PTX), achieving hepatocellular carcinoma-targeted delivery. The resulting NPs exhibited high drug loading capacity
Fang Wu et al.
Molecular pharmaceutics, 6(5), 1506-1517 (2009-07-30)
We aim to define the role of Kupffer cells in intrahepatic antigen presentation, using the selective delivery of antigen to Kupffer cells rather than other populations of liver antigen-presenting cells. To achieve this we developed a novel antigen delivery system
Chang-Moon Lee et al.
Magnetic resonance in medicine, 62(6), 1440-1446 (2009-10-28)
Hepatocyte-specific targeting agents are useful for evaluation of the hepatocytic function and the monitoring of disease progress. Superparamagnetic iron oxide nanoparticles (SPION) bearing terminal galactose groups exhibit a high affinity for the asialoglycoprotein receptor on the hepatocyte surface. In this
C Charloux et al.
Free radical biology & medicine, 19(5), 699-704 (1995-11-01)
Superoxide and hydroxyl free radicals are strongly implicated in the deleterious effects of reperfusion of grafted organs. Iron ions are critical in the Fenton-like reaction that generates oxygen-free radicals from H2O2. Using the ADP/Fe2+/H2O2 .OH-generating system, we demonstrated that components
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