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D8668

2′-Deoxyadenosine monohydrate

powder, BioReagent, suitable for cell culture

Synonym(s):

9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside

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Pack SizeSKUAvailabilityPrice
1 g
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CLP 85,900
5 g
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CLP 290,000

About This Item

Empirical Formula (Hill Notation):
C10H13N5O3 · H2O
CAS Number:
16373-93-6
Molecular Weight:
269.26
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
24894112
EC Number:
213-488-7
Beilstein/REAXYS Number:
91015
MDL number:
MFCD00005754
Assay:
≥99% (HPLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
H2O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
Storage temp.:
2-8°C

CLP 85,900

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biological source

synthetic (organic)

Quality Level

200

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

[H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3

InChI

1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1

InChI key

OLXZPDWKRNYJJZ-RRKCRQDMSA-N

Application

2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:
  • To study the importance of homologous recombination at the interface between replication and mitosis
  • To analyze deoxynucleoside-assisted transductions
  • To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells

2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.[1]

Biochem/physiol Actions

Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.

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This Item
D7400D0901D5287
2′-Deoxyadenosine monohydrate powder, BioReagent, suitable for cell culture

Sigma-Aldrich

D8668

2′-Deoxyadenosine monohydrate

2′-Deoxyadenosine monohydrate ≥99%

Sigma-Aldrich

D7400

2′-Deoxyadenosine monohydrate

2′-Deoxyguanosine monohydrate powder, BioReagent, suitable for cell culture, 99-100%

Sigma-Aldrich

D0901

2′-Deoxyguanosine monohydrate

2′-Deoxyinosine ≥98%

Sigma-Aldrich

D5287

2′-Deoxyinosine

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

assay

≥99% (HPLC)

assay

≥99%

assay

99-100%

assay

≥98%

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

−20°C

solubility

H2O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

1 M NH4OH: 50 mg/mL

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000552493
0000552493
0000508436
0000508435
0000508435

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Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells
Wilhelm T, et al.
Proceedings of the National Academy of Sciences of the USA, 111(2), 763-768 (2014)
MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer
Shukla S, et al.
Cancer Cell, 32(1), 71-87 (2017)
Pharmaceutical Chemistry, International Edition, 430-430 (2011)
View All Related Papers

Global Trade Item Number

SKUGTIN
D8668-1G04061833589823
D8668-5G04061833589830

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