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C9650

β-Cyano-L-alanine

≥95%, suitable for ligand binding assays

Synonym(s):

3-cyano-L-alanine

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Pack SizeSKUAvailabilityPrice
250 mg
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CLP 684,000

About This Item

Empirical Formula (Hill Notation):
C4H6N2O2
CAS Number:
Molecular Weight:
114.10
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:

CLP 684,000


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Product Name

β-Cyano-L-alanine, ≥95%

Quality Level

assay

≥95%

form

powder

technique(s)

ligand binding assay: suitable

color

white

mp

217 °C

storage temp.

−20°C

SMILES string

OC([C@@H](N)CC#N)=O

InChI

1S/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)/t3-/m0/s1

InChI key

BXRLWGXPSRYJDZ-VKHMYHEASA-N

Biochem/physiol Actions

β-Cyano-L-alanine (BCA) is used as a cystathione γ-lyase (CSE) inhibitor to study the physiological roles of hydrogen sulfide in processes such as angiogenesis and hypertension.

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This Item
146064A2010A1057
form

powder

form

powder, crystals or granules

form

powder

form

powder

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

assay

≥95%

assay

99%

assay

≥98% (TLC)

assay

≥98%

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

mp

217 °C

mp

202 °C (dec.) (lit.)

mp

256-258 °C (dec.) (lit.)

mp

-

color

white

color

white

color

colorless to white

color

white to off-white


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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R Miura et al.
Journal of biochemistry, 87(5), 1469-1481 (1980-05-01)
The reaction of D-amino acid oxidase [EC 1.4.3.3] (DAO) from porcine kidney with beta-cyano-D-alanine (D-BCNA) was studied. DAO was found to catalyze elimination of the cyano group as well as oxidation of D-BCNA. During the course of the reaction in
Ting-Ting Pan et al.
Journal of molecular and cellular cardiology, 40(1), 119-130 (2005-12-06)
The possible role of hydrogen sulfide (H2S) in cardioprotection was investigated in isolated rat ventricular myocytes exposed to severe metabolic inhibition (MI) in glucose-free buffer containing 2-deoxy-D-glucose (2-DOG), an inhibitor of glycolysis. Pretreatment (30 min) with NaHS (a H2S donor)
Liping Fang et al.
Journal of hypertension, 27(11), 2174-2185 (2009-08-01)
Recently, periadventitial adipose tissue (PAT) was found to secrete bioactive factors playing an important role in the regulation of vascular tension. Hydrogen sulfide (H(2)S), a novel cardiovascular gasotransmitter, relaxes vessels through the K(ATP) channel in a calcium-dependent and endothelial-independent manner.



Global Trade Item Number

SKUGTIN
C9650-250MG04061832423043

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