Unfortunately, we have no references reporting the molecular weight of peptidoglycan. Because it is not soluble without destroying the original structure, the molecular weight can not be determined by suitable analytical methods (GPC, viscosity, light scattering).
69554
Peptidoglycan from Bacillus subtilis
Synonym(s):
PGN
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 mg | Check Cart for Availability | CLP 275,000 |
About This Item
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|---|---|---|---|
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form solid | form lyophilized powder | form - | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
General description
Peptidoglycan.is a biopolymer that is a major component of the cell walls of Gram-positive bacteria. Peptidoglycan consists of a carbohydrate backbone of alternating units of N-acetyl glucosamine and N-acetyl muramic acid and is modified with both D- and L-amino acids. N-Acetyl muramic acid residues are cross-linked with oligopeptides. The terminal peptide is D-alanine although other amino acids are present as D-isomers.
Application
Peptidoglycan may be used for the activity estimation of lytic enzymes (e.g. lyticase). It is recommended to use a peptidoglycan concentration of 0.15-3 μg/ml in water or buffer and measuring at 450 nm. The peptidoglycan is not soluble but produces a suspension in water.
Peptidoglycan activates the Toll-like receptor 2 (TLR2), present in mammalian cells for the stimulation of lymphocytes. It may also function as an antagonist of Poly (I:C).
Peptidoglycan activates the Toll-like receptor 2 (TLR2), present in mammalian cells for the stimulation of lymphocytes. It may also function as an antagonist of Poly (I:C).
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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In the current study, a dimeric phenoloxidase (PO) from the hemolymph of healthy and diseased (pebrine infected) larvae of Antheraea assamensis Helfer was extracted and purified. The protein was subjected to purification using Sephacryl S-100 and CM Sepharose chromatography. The
Articles
Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.
Related Content
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 69554-10MG-F | 04061833278079 |
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What is the molecular weight of Product 69554, Peptidoglycan?
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Is Product 69554, Peptidoglycan, Gram positive or Gram negative?
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Peptidoglycan is Gram positive.
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What is the method of preparation of Product 69554, Peptidoglycan?
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Peptidoglycan is made by fermentation and so it is from vegetative cell bacteria. Peptidoglycan is from strain DSM 10.
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What is the solubility of Product 69554, Peptidoglycan?
1 answer-
Peptidoglycans are insoluble in all solvents. To increase the recovery of solubility, let the peptidoglycan soak in an aqueous buffer for several hours or overnight.
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