SRP8026
Annexin V human
recombinant, expressed in E. coli, GST tagged, ≥95% (SDS-PAGE)
Sinonimo/i:
Annexin A5, Calphobindin I, EC 2.7.1.23, Endonexin II, Placental anticoagulantprotein I
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100 μG
CHF 455.00
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Cambia visualizzazione
100 μG
CHF 455.00
About This Item
Codice UNSPSC:
12352200
NACRES:
NA.32
Prodotti consigliati
Origine biologica
human
Ricombinante
expressed in E. coli
Tag
GST tagged
Saggio
≥95% (SDS-PAGE)
Stato
lyophilized
PM
~52 kDa
Confezionamento
pkg of 100 μg
Condizioni di stoccaggio
avoid repeated freeze/thaw cycles
tecniche
activity assay: suitable
Colore
white
N° accesso UniProt
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... ANXA5(308)
Descrizione generale
Annexin V is a member of the annexin family of calcium and membrane-binding proteins that have anticoagulatory and anti-inflammatory properties. The encoded protein is 320 amino acid long and is folded into four domains, each having five α-helices, forming a superhelical globular structure. The ANX5 gene is mapped to human chromosome 4q26-q28 and spans a length of 28kb containing 13 exons and 12 introns.[1][2]
Applicazioni
Annexin V has been used to examine phosphorylation activity of ChaK1 (channel-kinase 1).[3]
Azioni biochim/fisiol
Annexins are a family of water-soluble proteins that bind to membranes and phospholipids in a calcium-dependent manner. They participate in several cellular functions, such as membrane fusion and cytoskeletal interaction. Annexin V is a potent anticoagulant and serves as a voltage-gated calcium channel when bound to membrane in vitro. It is found to inhibit phospholipase A2 and protein kinase C.[1][2][4]
Stato fisico
Lyophilized from PBS, pH 7.4.
Ricostituzione
Reconstitute with 100 μL deionized water.
Altre note
Recombinant human annexin V fused to a GST-tag.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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