SRP4304

NGF-beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Sinonimo/i: Nerve Growth Factor β, Ngf, Ngfb
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Origine biologica: mouse
• Ricombinante: expressed in E. coli
• Saggio: ≥98% (SDS-PAGE)
• Stato: lyophilized
• Potenza: 0.2 ng/mL ED₅₀
• PM: ~13.4 kDa
• Confezionamento: pkg of 20 μg
• Impurezze: endotoxin, tested
• N° accesso NCBI: P01139
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: mouse ... Ngf(18049)

Descrizione

Descrizione generale

Nerve growth factor-β (NGF-β) belongs to the neurotrophin family.[1] The active form of human NGF-β is a homodimer, non-glycosylated chain.[2]

Azioni biochim/fisiol

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells.[1] It brings pro-survival effects with the help of receptor tyrosine kinase TrkA.[3] NGF-β is associated with diabetic neuropathy and ischemic heart disease.[1] It is also involved in airway nerve system.[4] NGF-β is also responsible for the pain which is linked with osteoarthritis (OA).[5] It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.[6]

Stato fisico

Lyophilized without any additives.

Ricostituzione

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable