SML2162

Telithromycin

≥90% (HPLC), bacterial protein synthesis inhibitor, powder

• Sinonimo/i: (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[4-[4-(3-pyridinyl)-1H-imidazol-1-yl]butyl]-10-[[3,4,6-trideoxy-3-dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone
• Formula empirica (notazione di Hill): C₄₃H₆₅N₅O₁₀
• Numero CAS: 191114-48-4
• Peso molecolare: 812.00
• NACRES: NA.77
• UNSPSC Code: 12352200
• EC Number: 682-750-4
• MDL number: MFCD00943561
• Assay: ≥90% (HPLC)
• Form: powder

Proprietà

• Nome del prodotto: Telithromycin, ≥90% (HPLC)
• assay: ≥90% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C(N1CCCCN2C=NC(C3=CC=CN=C3)=C2)O[C@]4([C@@]1([H])[C@H](C([C@@H](C[C@]([C@@H]([C@H](C([C@H](C(O[C@@H]4CC)=O)C)=O)C)O[C@H]5[C@@H]([C@H](C[C@H](O5)C)N(C)C)O)(OC)C)C)=O)C)C
• InChI: 1S/C43H65N5O10/c1-12-33-43(8)37(48(41(53)58-43)19-14-13-18-47-23-31(45-24-47)30-16-15-17-44-22-30)27(4)34(49)25(2)21-42(7,54-11)38(28(5)35(50)29(6)39(52)56-33)57-40-36(51)32(46(9)10)20-26(3)55-40/h15-17,22-29,32-33,36-38,40,51H,12-14,18-21H2,1-11H3/t25-,26-,27+,28+,29-,32+,33-,36-,37-,38-,40+,42-,43-/m1/s1
• InChI key: LJVAJPDWBABPEJ-PNUFFHFMSA-N

Descrizione

Biochem/physiol Actions

Ketolide antibiotic

Telithromycin is a ketolide antibiotic, the first to enter clinical use. It is used to treat mild to moderate respiratory infections. Telithromycin binds to the subunit 50S of the bacterial ribosome, interfering with bacterial protein synthesis.

Informazioni sulla sicurezza

• pictograms: GHS08
• signalword: Danger
• hcodes: H370
• pcodes: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Hazard Classifications: STOT SE 1
• target_organs: Liver,Eyes
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable