Unfortunately, the stability of this product once resuspended has not been determined.
SML2148
Sulfo-N-succinimidyl Oleate sodium
≥95% (HPLC), fatty acid translocase inhibitor, powder
Sinonimo/i:
(Z)-1-(oleoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid, sodium salt, (Z)-2,5-Dioxo-1-[(1-oxo-9-octadecenyl)oxy]-3-pyrrolidinesulfonic acid, sodium salt, 2,5-Dioxo-1-[[(9Z)-1-oxo-9-octadecenyl]oxy]-3-pyrrolidinesulfonic acid, sodium salt, SSO sodium salt, Sulfosuccinimidyl oleate sodium
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Cambia visualizzazione
| A voi/SKU | Disponibilità | Prezzo |
|---|---|---|
5 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 127.00 |
25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 513.00 CHF 436.05 |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C22H36NO7S· Na
Numero CAS:
Peso molecolare:
481.58
NACRES:
NA.77
UNSPSC Code:
51111800
EC Number:
801-756-1
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
Sulfo-N-succinimidyl Oleate sodium, ≥95% (HPLC)
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
−20°C
SMILES string
CCCCCCCC/C=C\CCCCCCCC(ON1C(C(CC1=O)S([O-])(=O)=O)=O)=O.[Na+]
InChI
1S/C22H37NO7S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(25)30-23-20(24)18-19(22(23)26)31(27,28)29;/h9-10,19H,2-8,11-18H2,1H3,(H,27,28,29);
InChI key
IENDXPSKPJDQKO-UHFFFAOYSA-N
Application
Biochem/physiol Actions
Covalently modifies fatty acid translocase (CD36/FAT) Lys164 and irreversibly inhibits CD36-dependent FA uptake in vitro and in vivo.
Sulfo-N-succinimidyl oleate (SSO; Sulfosuccinimidyl oleate) inhibits fatty acid translocase (CD36/FAT)-mediated signaling as well as long-chain fatty acid (LCFA) and oxidized low density lipoproteins (oxLDL) uptake in an irreversible manner via covalent modification of CD36 Lys164 within its FA- and oxLDL-binding domain. SSO is employed both in cultures (5-500 μM) and in animals in vivo (40 mg/kg i.p.) for studying CD36-mediated cellular and physiological functions.
SSO is an inhibitor of the respiratory chain happening in mitochondria. SSO targets the lysine 164 residue of the fatty acid binding site, observed in CD36 (cluster of differentiation 36), a scavenger receptor.
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Questo articolo | |||
|---|---|---|---|
| description ≥95% (HPLC) | description ≥99% | description ≥95% (capillary GC) | description ≥82% (fatty acids), powder |
| assay ≥95% (HPLC) | assay ≥99% | assay ≥95% (capillary GC) | assay ≥82% (fatty acids) |
| form powder | form powder | form powder | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. room temp |
| storage condition desiccated | storage condition - | storage condition - | storage condition - |
| solubility DMSO: 2 mg/mL, clear (warmed) | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
Classe di stoccaggio
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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After I resuspend this product ( SML2148)in DMSO, how should I store the solution? Aliquot and store at -20C?
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