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Unfortunately, we do not determine the conformation of this product.
SML0982
Astaxanthin
from Blakeslea trispora, ≥97% (HPLC), powder, PPARγ
Sinonimo/i:
3,3′-Dihydroxy-β-carotene-4,4′-dione, trans-Astaxanthin
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50 MG
CHF 147.00
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50 MG
CHF 147.00
About This Item
Formula empirica (notazione di Hill):
C40H52O4
Numero CAS:
Peso molecolare:
596.84
Codice UNSPSC:
12352200
NACRES:
NA.77
Prodotti consigliati
Nome del prodotto
Astaxanthin, ≥97% (HPLC), from Blakeslea trispora
Origine biologica
Blakeslea trispora
Saggio
≥97% (HPLC)
Stato
powder
Condizioni di stoccaggio
desiccated
protect from light
Colore
, pink to very dark purple
Solubilità
DMSO: 1 mg/mL (warmed)
Temperatura di conservazione
−20°C
Stringa SMILE
O[C@H]1CC(C(=C(C1=O)C)\C=C\C(=C\C=C\C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C2=C(C(=O)[C@H](CC2(C)C)O)C)\C)\C)(C)C
InChI
1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1
MQZIGYBFDRPAKN-UWFIBFSHSA-N
Descrizione generale
Astaxanthin (AST) is a red dietary carotenoid. It is mainly found in aquatic animals and microalgae, such as Haematococcus pluvialis and Chlorella zofingiensis.[1]
Applicazioni
Astaxanthin has been used:
- as an antioxidant to study its effect on Brachionus manjavacas (Rotifera) population growth[2]
- to study its effects on the treatment of diabetic retinopathy.[2][3]
- to investigate its role in restoring the expression of Nrf2 (nuclear factor erythroid 2 p45-related factor 2) and glutathione S-transferase P1 (GSTP1) through epigenetic modification in human prostate LNCaP cells.[1]
Azioni biochim/fisiol
In vivo and in vitro studies propose that astaxanthin (AST) possesses health-promoting activities, signifying its potential use in the prevention of various diseases, such as cancers and Parkinson′s disease.[1] Due to its bright red colour, AST has been used as a food colorant in animal feeds.[3]
Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity.
Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory compounds nitric oxide, prostaglandin E2, TNF-α, and interleukin-1β. Astaxanthin′s protection of cells from oxidative stress generated by TNF-α and palmitate has been shown to ameliorate insulin resistance. Astaxanthin has also been shown to be an inhibitor of PPARγ.
Altre note
Light and air sensitive
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I clienti hanno visto anche
Effects of astaxanthin on Brachionus manjavacas (Rotifera) population growth.
Johnston R K, et al.
Aquaculture Research, 49(6), 2278-2287 (2018)
Shreya Agrawal et al.
Plant physiology (2021-10-09)
The high-value carotenoid astaxanthin (3,3'-dihydroxy-β,β-carotene-4,4'-dione) is one of the most potent antioxidants in nature. In addition to its large-scale use in fish farming, the pigment has applications as a food supplement and an active ingredient in cosmetics and in pharmaceuticals
Effect of astaxanthin on retinal pigment epithelial cells in high glucose: an in-vitro study.
Fu D and Tian X, et al.
Biomedical Research, 28(15) (2017)
Epigenetic CpG methylation of the promoter and reactivation of the expression of GSTP1 by Astaxanthin in human prostate LNCaP cells.
Yang Y, et al.
The AAPS Journal, 19(2), 421-430 (2017)
Huilin Liu et al.
Marine drugs, 17(3) (2019-03-22)
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide. It is a complex process, including a broad spectrum of hepatic lesions from fibrosis to cirrhosis. Our previous study suggested that astaxanthin (AST) could alleviate the hepatic
Articoli
DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research
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Is the Astaxanthin SML0982 in the 3S, 3'S conformation or is it a mix?
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