SAB4502896

Anti-CD147, C-Terminal antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: BASI, CD147, basigin, basigin (Ok blood group), collagenase stimulatory factor
• Numero MDL: MFCD02262857
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 42 kDa
• Reattività contro le specie: mouse, human, rat
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• N° accesso NCBI: P35613
• N° accesso UniProt: P35613
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... BSG(682)

Descrizione

Descrizione generale

Anti-CD147 Antibody detects endogenous levels of total CD147 protein.
Cluster of differentiation 147 (CD147) is a multifunctional trans-membrane glycoprotein and is a member of the immunoglobulin superfamily. It occurs in transmembrane and soluble forms. CD147 is also known as EMMPRIN or basigin (BSG). It is a 57 kDa glycoprotein with two extracellular Ig domains. CD147 is located on human chromosome 19p13.

Immunogeno

The antiserum was produced against synthesized peptide derived from human CD147.

Immunogen Range: 336-385

Applicazioni

Anti-CD147, C-Terminal antibody has been used in western blotting.

Azioni biochim/fisiol

Cluster of differentiation 147 (CD147) is considered as an extracellular matrix metalloproteinase inducer. It participates in several physiological and pathological activities, mainly in tumor invasion and metastasis. CD147 helps in tumor cell-macrophage interactions and stimulates MMPs (matrix metalloproteinases) and vascular endothelial growth factor (VEGF).

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable