S1270

β-Sitosterol

synthetic, ≥95%

• Sinonimo/i: beta-Sitosterol, α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterol, 5-Stigmasten-3β-ol
• Formula empirica (notazione di Hill): C₂₉H₅₀O
• Numero CAS: 83-46-5
• Peso molecolare: 414.71
• Beilstein: 1916165
• Numero CE: 201-480-6
• Numero MDL: MFCD00003631
• Codice UNSPSC: 12352211
• ID PubChem: 24899468
• NACRES: NA.77

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 100
• Saggio: ≥95%
• Stato: powder
• Punto di fusione: 136-140 °C (lit.)
• Gruppo funzionale: hydroxyl
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@H](C(C)C)CC
• InChI: 1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1; KZJWDPNRJALLNS-VJSFXXLFSA-N

Descrizione

Applicazioni

β-Sitosterol has been used:

• to study its ability to improve the suitability of two pollens[1]
• as a standard in the determination of sterol purities[2]
• as a standard in quantitative genetic analysis[3]
• as a standard in the estimation of plant sterols[4]

Azioni biochim/fisiol

A phytosterol with structure very similar to cholesterol that exhibits estrogenic activity. Inhibits proliferation of human leukemia cells, with G2/M arrest, endoreduplication, and polymerization of α-tubulin and microtubules.[5]

Increased β-sitosterol administration displaces cholesterol during absorption. This elevates fecal secretion.[6] It is known to regulate intestinal immunity.[7]

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)