P0869

Monoclonal Anti-Peroxisome Proliferator Activated Receptor α antibody produced in mouse

~1 mg/mL, clone 3B6/PPAR, purified immunoglobulin, buffered aqueous solution

• Sinonimo/i: Anti-PPARα
• Numero MDL: MFCD01092469
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 200
• Coniugato: unconjugated
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 3B6/PPAR, monoclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: mouse, rat, human
• Concentrazione: ~1 mg/mL
• tecniche: western blot: 2-5 μg/mL using human, mouse and rat
• Isotipo: IgG2b
• N° accesso UniProt: Q07869
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... PPARA(5465) ; mouse ... Ppara(19013) ; rat ... Ppara(25747)

Descrizione

Descrizione generale

Peroxisome proliferator-activated receptors (PPARs) are a group of closely related nuclear receptors. Three PPAR isotypes have been identified: α,β (also called NUC1) and γ. PPARa mRNA is expressed most in brown adipose tissue, heart, liver and kidney in rats. The gene encoding PPARα is localized on human chromosome 22q12-q13.1 and rat chromosome 7q34.

Immunogeno

purified recombinant PPARα protein.

Azioni biochim/fisiol

Peroxisome proliferator-activated receptors (PPARs) may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. PPARα has a protective function in fatty acids overload associated tubular injury. The enzyme also has a role in fatty acid oxidation and metabolism.

Stato fisico

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable