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MAK433

Sigma-Aldrich

Adenosine Quantification Assay Kit

sufficient for 100 fluorometric tests

Sinonimo/i:

Adenosine Test Kit

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12161503
NACRES:
NA.84

Livello qualitativo

impiego

sufficient for 100 fluorometric tests

input

plasma

Metodo di rivelazione

fluorometric

Malattie correlate

cancer; neurological disorders; cardiovascular diseases

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Descrizione generale

Adenosine is a purine nucleoside base, which is the precursor of adenosine triphosphate, or ATP, and is utilized thoroughly throughout the entire body in general metabolism. Extracellular adenosine acts as a local modulator with a generally cytoprotective function in the body. Its effects on tissue protection and repair fall into four categories: increasing the ratio of oxygen supply to demand; protecting against ischaemic damage by cell conditioning; triggering anti-inflammatory responses; and the promotion of angiogenesis.

Applicazioni

The Adenosine Quantification Assay Kit may be used for:
  • Cancer Research
  • Cardiovascular Disease Research
  • Neurological Disease Research

Caratteristiche e vantaggi

  • Supportive calculator (Click here to download a calculator excel file) Analyze results based on your experimental data!
  • Quick instruction bench card - to assure your experimental success
  • More experiments in one kit - contains sufficient reagents for 100 tests

Compatibilità

The kit is suitable for the quantification of adenosine in plasma.

Principio

The Adenosine Quantification Assay Kit provides a simple and quick fluorometric method for the detection of adenosine. The kit is based on a multi-step enzymatic approach, resulting in the formation of fluorescent product that is measured at λEx = 550 nm/λEm = 585. The kit has a linear range of 0 to 20 μM.

Altre note

For additional information on our range of Biochemicals, please complete this form.

Codice della classe di stoccaggio

10 - Combustible liquids


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Adenosine receptors as therapeutic targets.
Jacobson K A, et al.
Nature Reviews. Drug Discovery, 5(3), 247-264 (2006)
B B Fredholm et al.
Pharmacological reviews, 53(4), 527-552 (2001-12-06)
Four adenosine receptors have been cloned and characterized from several mammalian species. The receptors are named adenosine A(1), A(2A), A(2B), and A(3). The A(2A) and A(2B) receptors preferably interact with members of the G(s) family of G proteins and the
Monika Samsel et al.
Postepy higieny i medycyny doswiadczalnej (Online), 67, 1189-1203 (2014-01-01)
Adenosine is an endogenous purine nucleoside that plays an important role in many biochemical processes. It acts through the four types of adenosine receptors: A1, A2A, A2B, A3 which are located i.a. in the immune, nervous, circulatory, respiratory or urinary

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