Passa al contenuto
Merck
Tutte le immagini(2)

Documenti fondamentali

M1778

Sigma-Aldrich

Mucina

Type III, bound sialic acid 0.5-1.5 %, partially purified powder

Sinonimo/i:

MUC

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali

Scegli un formato

10 G
CHF 95.90
100 G
CHF 479.00

CHF 95.90


Spedizione prevista il01 giugno 2025


Richiedi un ordine bulk

Scegli un formato

Cambia visualizzazione
10 G
CHF 95.90
100 G
CHF 479.00

About This Item

Numero CAS:
Numero CE:
Numero MDL:
Codice UNSPSC:
12352202
NACRES:
NA.61

CHF 95.90


Spedizione prevista il01 giugno 2025


Richiedi un ordine bulk

Origine biologica

Porcine stomach

Tipo

Type III

Stato

partially purified powder

Composizione

bound sialic acid, 0.5-1.5%

tecniche

microbiological culture: suitable

Solubilità

NaOH: soluble 20 mg/mL

Temperatura di conservazione

2-8°C

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus.[1] It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.[2]

Applicazioni

Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.[3]

Azioni biochim/fisiol

Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.[4]

Nota sulla preparazione

Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 5

1 of 5

Kenny C Mok et al.
mBio, 11(6) (2020-12-10)
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use
Leyuan Li et al.
Microbiome, 8(1), 33-33 (2020-03-13)
Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
C A Saceanu et al.
Journal of clinical microbiology, 31(9), 2371-2374 (1993-09-01)
Early identification and isolation of tuberculosis patients is of utmost importance to minimize the risk of further epidemic spread of the disease. The traditional concentrated acid-fast smears are not very reliable tools for the presumptive diagnosis of tuberculosis. Acid-fast bacillus
Francisco J Alvarez et al.
Applied and environmental microbiology, 81(8), 2770-2780 (2015-02-11)
The pathogenic fungus Candida albicans is the leading cause of vulvovaginal candidiasis (VVC). VVC represents a major quality-of-life issue for women during their reproductive years, a stage of life where the vaginal epithelium is subject to periodic hormonally induced changes
Jonathan E Phillips et al.
Journal of pharmacological and toxicological methods, 53(2), 160-167 (2006-03-02)
A method to measure the mucin concentration in bronchoalveolar lavage (BAL) fluid was developed to aid efforts to identify pharmacologically the mechanisms that modulate pathophysiological mucin secretion. Mucins are the major macromolecular components of mucus. In the airways, mucus is

Articoli

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

Questions

1–7 of 7 Questions  
  1. Can I reconstitute the mucin so that it forms a saliva/snot-like substance? I can't seem to find any papers that have done this...

    1 answer
    1. Mucins are soluble in water, forming hazy viscous solutions.

      Helpful?

  2. What does the "Type" designation in Mucin from porcine stomach mean?

    1 answer
    1. The type designation does not have any particular biological significance.  It is used to emphasize differences in the listings of this product.

      Helpful?

  3. What are the differences between Mucin from porcine stomach Products M2378 and M1778?

    1 answer
    1. Product No. M2378 is a crude mucin preparation. Product No. M1778 is a partially purified powder prepared according to the method described in Glenister, D.A. and Salmon. K. Microbial Ecol. in Health & Disease 1, 31, (1988). The amount of bound sialic acids are also different. Please refer to the specification sheets on our website.

      Helpful?

  4. Is Product M1778, Mucin from porcine stomach, a purified preparation of mucin?

    1 answer
    1. This product is a partially purified preparation of mucin based on the method of Glenister cited on the product's webpage.

      Helpful?

  5. What is the molecular weight of Product M1778, Mucin from porcine stomach?

    1 answer
    1. This product is partially purified from crude mucin, M2378.  Sigma has not determined the molecular weight of this product. Neither has the sugar and amino acid composition been determined.

      Helpful?

  6. How can I solubilize Product M1778, Mucin from porcine stomach?

    1 answer
    1. Mucin is not readily soluble in aqueous solutions. Turbid "solutions" will form at about 5 mg/mL in 0.1 M acetate buffer, pH 5.0. To try to increase the solubility, one might try further dilution and sonication, but we have not tried this in our labs.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

Reviews

No rating value

Active Filters

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.