G1514

D-(+)-Glucosamine hydrochloride

≥99%, BioReagent, suitable for cell culture

• Sinonimo/i: 2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride
• Formula empirica (notazione di Hill): C₆H₁₃NO₅ · HCl
• Numero CAS: 66-84-2
• Peso molecolare: 215.63
• Beilstein: 4157370
• Numero CE: 200-638-1
• Numero MDL: MFCD00135831
• Codice UNSPSC: 12352209
• ID PubChem: 24895066
• NACRES: NA.75

Proprietà

• Origine biologica: Aspergillus niger; maize fruit
• Livello qualitativo: 200
• Nome Commerciale: BioReagent
• Saggio: ≥99%
• Stato: powder
• tecniche: cell culture | mammalian: suitable
• Punto di fusione: 190-194 °C (dec.) (lit.)
• Solubilità: water: 100 mg/mL, clear, colorless
• Stringa SMILE: Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1; QKPLRMLTKYXDST-NSEZLWDYSA-N

Descrizione

Descrizione generale

Glucosamine, an amino sugar is generated form glucose and glutamine[1] and is naturally produced in the body.[2] Glucosamine, a endogenous amino monosaccharide[2] is the major source of glucosamine-6-phosphate and n-acetylglucosamine.[1]

Applicazioni

Glucosamine has been used as a standard to examine the concentration of glucosamine in the synovial fluid and its pharmacokinetics in serum.[3]

Azioni biochim/fisiol

Glucosamine is preferred as a nutritional supplement for individuals with osteoarthritis.[4] It is used as a building block for the production of proteoglycans and glycosaminoglycans.[2]

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)