A3286

N-acetil-D-glucosammina

BioReagent, suitable for cell culture

• Sinonimo/i: 2-acetamido-2-desossi-D-glucosio, D-GlcNAc
• Formula empirica (notazione di Hill): C₈H₁₅NO₆
• Numero CAS: 7512-17-6
• Peso molecolare: 221.21
• UNSPSC Code: 12352201
• NACRES: NA.75
• PubChem Substance ID: 24890757
• EC Number: 231-368-2
• Beilstein/REAXYS Number: 1727589
• MDL number: MFCD00061615

Proprietà

• product line: BioReagent
• Quality Segment: 200
• assay: ≥95% (HPLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 211 °C (dec.) (lit.)
• application(s): advanced drug delivery
• storage temp.: −20°C
• SMILES string: CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1
• InChI key: OVRNDRQMDRJTHS-RTRLPJTCSA-N

Descrizione

General description

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.[1]

Application

N-Acetyl-D-glucosamine addition has been used:

• as a substrate to develop dot-blots
• as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis[1]
• to detect specific immune complexes in western blot analysis

Biochem/physiol Actions

N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity. GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.[1]

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)