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G1166

Sigma-Aldrich

Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse

clone GAD-6, purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

Anti-GAD 65

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

GAD-6, monoclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

mammals (and some lower vertebrates)

tecniche

immunohistochemistry: 1:100-1:500
western blot: 1:1,000-1:5,000

Isotipo

IgG2a

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... GAD2(2572)
mouse ... Gad2(14417)

Specificità

Recognizes the lower molecular weight isoform of the two GAD isoforms identified in brain, GAD 65. Can be used for immunochemical localization of GABA secreting neurons.

Immunogeno

purified rat brain GAD 65.

Stato fisico

Solution in 0.01 M phosphate buffered saline, containing 0.04% sodium azide.

Nota sulla preparazione

Purified using Protein A chromatography.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Stathis S Leondopulos et al.
Journal of neural engineering, 9(2), 026015-026015 (2012-03-01)
Slow wave oscillations in the brain are essential for coordinated network activity but have not been shown to self-organize in vitro. Here, the development of dissociated hippocampal neurons into an active network with oscillations on multi-electrode arrays was evaluated in
Han-Byeol Kim et al.
Cell death discovery, 6, 73-73 (2020-08-21)
Neonatal maternal separation (NMS), as an early-life stress (ELS), is a risk factor to develop emotional disorders. However, the exact mechanisms remain to be defined. In the present study, we investigated the mechanisms involved in developing emotional disorders caused by
Rossella De Cegli et al.
Nucleic acids research, 41(2), 711-726 (2012-11-28)
Gene expression profiles can be used to infer previously unknown transcriptional regulatory interaction among thousands of genes, via systems biology 'reverse engineering' approaches. We 'reverse engineered' an embryonic stem (ES)-specific transcriptional network from 171 gene expression profiles, measured in ES
Azadeh Yazdan-Shahmorad et al.
eLife, 7 (2018-05-29)
Brain stimulation modulates the excitability of neural circuits and drives neuroplasticity. While the local effects of stimulation have been an active area of investigation, the effects on large-scale networks remain largely unexplored. We studied stimulation-induced changes in network dynamics in
Nelyane N M Santana et al.
Frontiers in neuroanatomy, 12, 36-36 (2018-06-06)
In mammals, the suprachiasmatic nucleus (SCN) and the intergeniculate leaflet (IGL) are the main components of the circadian timing system. The SCN, classically known as the master circadian clock, generates rhythms and synchronizes them to environmental cues. The IGL is

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