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F8890

Sigma-Aldrich

Folic acid

BioReagent, suitable for plant cell culture, ≥97%

Sinonimo/i:

PteGlu, Pteroyl-L-glutamic acid, Vitamin M

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About This Item

Formula empirica (notazione di Hill):
C19H19N7O6
Numero CAS:
59-30-3
Peso molecolare:
441.40
Beilstein:
100781
Numero CE:
200-419-0
Numero MDL:
MFCD00079305
Codice UNSPSC:
12352200
eCl@ss:
34058014
ID PubChem:
24894979

Nome Commerciale

BioReagent

Saggio

≥97%

tecniche

cell culture | plant: suitable

applicazioni

agriculture

Stringa SMILE

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
OVBPIULPVIDEAO-LBPRGKRZSA-N

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Descrizione generale

Folic acid is a vitamin that is reduced to dihydrofolate in vivo. Dihydrofolate is further reduced tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SLBC2647V
081M1546V
070M1627V
098K0082
010M1567

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Tor A Strand et al.
Pediatrics, 135(4), e918-e926 (2015-03-25)
Folate and vitamin B-12 are important for growth. Many children in low- and middle-income countries have inadequate intakes of these nutrients. We undertook a randomized, placebo controlled double-blind trial in 1000 North Indian children, 6 to 35 months of age
Séverine Ledoux et al.
Annals of surgery, 259(6), 1104-1110 (2014-05-14)
To study long-term nutritional deficits based on adherence to a standardized nutritional care after gastric bypass (GBP). Long-term prospective data on nutritional complications after GBP are missing. It is not known whether severe deficiencies are prevented by standard multivitamin supplementation
Breige McNulty et al.
The American journal of clinical nutrition, 98(1), 92-98 (2013-05-31)
Supplementation with folic acid (FA) is recommended worldwide before and during early pregnancy because of its proven effect in preventing neural tube defects, but the role of FA after the 12th gestational week (GW) is much less clear. We investigated
Tihomir Tomasić et al.
Bioorganic & medicinal chemistry letters, 19(1), 153-157 (2008-11-19)
Mur ligases catalyze the biosynthesis of the UDP-MurNAc-pentapeptide precursor of peptidoglycan, an essential polymer of bacterial cell-wall. They constitute attractive targets for the development of novel antibacterial agents. Here we report on the synthesis of a series of 2,4-diaminoquinazolines, quinazoline-2,4(1H,3H)-diones
R Wendel Naumann et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(35), 4400-4406 (2013-10-16)
Vintafolide (EC145) is a folic acid-desacetylvinblastine conjugate that binds to the folate receptor (FR), which is expressed on the majority of epithelial ovarian cancers. This randomized phase II trial evaluated vintafolide combined with pegylated liposomal doxorubicin (PLD) compared with PLD
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