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Documenti fondamentali

A2780 Cell Line human

93112519, human ovary, Epithelial

Sinonimo/i:

A-2780 Cells

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About This Item

Codice UNSPSC:
41106514
Prezzi e disponibilità al momento non sono disponibili

Nome del prodotto

A2780 Cell Line human, ovarian carcinoma, 93112519

Origine biologica

human ovary

Modalità di accrescimento

Adherent

Cariotipo

Not specified

Morfologia

Epithelial

Prodotti

Not specified

Recettori

Not specified

tecniche

cell culture | mammalian: suitable

Malattie correlate

cancer

Condizioni di spedizione

dry ice

Temperatura di conservazione

−196°C

Origine della linea cellulare

Human ovarian carcinoma

Descrizione della linea cellulare

The A2780 human ovarian cancer cell line was established from tumour tissue from an untreated patient. Cells grow as a monolayer and in suspension in spinner cultures. A2780 is the parent line to the cisplatin resistant cell line A2780 cis (Sigma catalogue no. 93112517) and the adriamycin resistant cell line A2780 ADR (Sigma catalogue no. 93112520).

Applicazioni

A2780 cell line human is used in toxicity testing and cancer genetic studies.
A2780 cell line human has been used to:
  • study the role of Snail and Slug in ovarian tumor neovascularization[1]
  • overcome cisplatin resistance in ovarian cancer cells using liposome application[2]
  • demonstrate the significance of NMDA (N-methyl-D-aspartate) receptors as targets for treatment of ovarian cancers[3]
  • study the effect of low molecular weight heparin tinzaparin on cisplatin resistance in ovarian cancer cells[4]

Profilo DNA

STR-PCR Data: Amelogenin: X
CSF1PO: 10,11
D13S317: 12,13
D16S539: 11,13
D5S818: 11,12
D7S820: 10
THO1: 6
TPOX: 8,10
vWA: 15,16

Terreno di coltura

Mantenimento delle subcolture

Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 3-6x10,000cells/cm2 using 0.05% Trypsin or Trypsin/EDTA; 5% CO2; 37°C.

Altre note

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

Esclusione di responsabilità

This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.

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Certificati d'analisi (COA)

Lot/Batch Number

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Questions

  1. Do these samples come with any pathogen testing certifications. If so, do you make them accessible on your WEB site? If so, where might I find them.

    1 answer
    1. This product is supplied by ECACC. Sterility and mycoplasma testing is performed on each lot. See below for a link to a sample Certificate of Analysis (lot 21C003) issued by ECACC:
      https://www.culturecollections.org.uk/search/cofa.jsp

      For additional information please review the product page at the ECACC website:
      https://www.culturecollections.org.uk/products/celllines/generalcell/detail.jsp?refId=93112519&collection=ecacc_gc.

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