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C5423

Sigma-Aldrich

Clenbuterol hydrochloride

≥95% (TLC), powder, β2-adrenoceptor agonist

Sinonimo/i:

4-Amino-α-(t-butylaminomethyl)-3,5-dichlorobenzyl alcohol hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C12H18Cl2N2O · HCl
Numero CAS:
21898-19-1
Peso molecolare:
313.65
Numero CE:
244-643-7
Numero MDL:
MFCD00083280
Codice UNSPSC:
12352200
ID PubChem:
24892782
NACRES:
NA.77

product name

Clenbuterol hydrochloride, ≥95%

Saggio

≥95%

Forma fisica

powder

drug control

Home Office Schedule 4.2

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1

InChI

1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H
OPXKTCUYRHXSBK-UHFFFAOYSA-N

Informazioni sul gene

human ... ADRB2(154)

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Applicazioni

Clenbuterol hydrochloride has been used:
  • as an agonist for β-adrenergic receptor (β-AR) from chick skeletal muscle
  • to induce hypertrophic effects in masseter, digastric, and temporalis muscles of rat
  • as a reference β-agonist standard in tandem mass spectrometry(MS-MS)

Azioni biochim/fisiol

Clenbuterol hydrochloride is a β2-adrenoceptor agonist and bronchodilator. It is effective in improving peak expiratory flow rate (PEFR) in asthma patients. Clenbuterol is also a performance-enhancing drug as it stimulates the central nervous system and improves oxygen transport. Clenbuterol elicits cardio protective functionality in patients with dilated cardiomyopathy.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

G004337

HPLC Analysis of Beta-Receptor Agonist Enantiomers on Astec® CHIROBIOTIC® T, application for HPLC

G004431

LC/MS Analysis of Clenbuterol In Plasma on Astec® CHIROBIOTIC® T with Phospholipid Removal using HybridSPE® Phospholipid, application for SPE, application for LC-MS

G004245

LC/MS Analysis of Clenbuterol Enantiomers in Plasma on Astec® CHIROBIOTIC® T after SPE using HybridSPE®-Phospholipid, application for HPLC

G004493

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® T, application for HPLC

G004596

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® T2, application for HPLC

G004621

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® V, application for HPLC

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H351,H360FD

Classi di pericolo

Carc. 2 - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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C A Izeboud et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 48(9), 497-502 (1999-10-16)
To investigate the suppressive effects of the beta-agonist clenbuterol on the release of TNF-alpha and IL-6 in a lipopolysaccharide (LPS)-model of inflammation, both in vitro and in vivo. Human U-937 cell line (monocyte-derived macrophages), and male Wistar rats (200-250 g).
A trial of clenbuterol in bronchial asthma.
Anderson G and Wilkins E
Thorax, 32(6), 717-719 (1977)
Jelka Pleadin et al.
Meat science, 86(3), 733-737 (2010-07-30)
The aim of this study was to determine the level of clenbuterol residues in muscle tissue of pigs after repeat administration in a growth-promoting dose. An anabolic dose of clenbuterol (20 μg/kg body mass per day) was administered orally to
I Semkova et al.
Brain research. Brain research reviews, 30(2), 176-188 (1999-10-19)
Neurotrophins and other neurotrophic factors have been shown to support the survival and differentiation of many neuronal populations of the central and peripheral nervous system. Therefore, administering neurotrophic factors could represent an alternative strategy for the treatment of acute and
Vipin Arora et al.
Molecular pain, 17, 1744806921997206-1744806921997206 (2021-04-09)
Beta 2 adrenergic receptor (β2 AR) activation in the central and peripheral nervous system has been implicated in nociceptive processing in acute and chronic pain settings with anti-inflammatory and anti-allodynic effects of β2-AR mimetics reported in several pain states. In
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