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C5108

Sigma-Aldrich

Cathepsin G from human sputum

≥0.2 units/mg protein, salt-free, lyophilized powder

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About This Item

Numero CAS:
Classificazione EC (Enzyme Commission):
Numero MDL:
Codice UNSPSC:
12352200
NACRES:
NA.32

Origine biologica

human sputum

Forma fisica

salt-free, lyophilized powder

Attività specifica

≥0.2 units/mg protein

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Informazioni sul gene

human ... CTSG(1511)

Azioni biochim/fisiol

Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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E D Son et al.
Dermatology (Basel, Switzerland), 224(4), 352-360 (2012-07-05)
Cathepsin G, a serine protease that is activated by ultraviolet (UV) radiation, increases matrix metalloproteinase-1 (MMP-1) expression in fibroblasts through fibronectin (Fn) fragmentation and promotes the conversion of proMMP-1 to active MMP-1. This study investigated whether [2-[3-[[(1-benzoyl-4-piperidinyl)methylamino]carbonyl]-2-naphthalenyl]-1-(1-naphthalenyl)-2-oxoethyl]-phosphonic acid (KPA), a
Jeppe Thorlacius-Ussing et al.
Journal of cancer research and clinical oncology, 145(2), 383-392 (2018-11-24)
Elastin is a signature protein of lungs. Increased elastin turnover driven by altered proteolytic activity is an important part of lung tumorigenesis. Elastin-derived fragments have been shown to be pro-tumorigenic, however, little is known regarding the biomarker potential of such
Jing Zhang et al.
Traffic (Copenhagen, Denmark), 13(5), 745-757 (2012-01-31)
Rabankyrin-5 (Rank-5) has been implicated as an effector of the small GTPase Rab5 and plays an important role in macropinocytosis. We have now identified Rank-5 as an interaction partner for the recycling regulatory protein, Eps15 homology domain 1 (EHD1). We
Dieke van der Windt et al.
FEMS immunology and medical microbiology, 66(3), 445-448 (2012-09-05)
Although the Streptococcus pneumoniae polysaccharide capsule is an important virulence factor, ~ 15% of carriage isolates are nonencapsulated. Nonencapsulated S. pneumoniae are a cause of mucosal infections. Recent studies have shown that neutrophils kill S. pneumoniae predominately through neutrophil proteases, such as elastase
Alyssa D Gregory et al.
The Journal of biological chemistry, 287(42), 35341-35350 (2012-08-24)
Neutrophil elastase (NE) is a neutrophil-derived serine proteinase with broad substrate specificity. We have recently demonstrated that NE is capable of entering tumor cell endosomes and processing novel intracellular substrates. In the current study, we sought to determine the mechanism

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